A. Prevalent diabetes
|
Metabolic syndrome
definition
|
Prevalence of metabolic syndrome (n/N,%)
|
Prevalence of diabetes (n/N,%)
|
|
Specificity
|
|
WHO, WHR ³ 0.91
|
250/1005 (24.9%)
|
47/1005 (4.7%)
|
0.83
|
0.78
|
|
WHO, waist ³ 94 cm
|
212/1005 (21.1%)
|
47/1005 (4.7%)
|
0.68
|
0.81
|
|
NCEP, waist >102 cm
|
138/1005 (13.7%)
|
47/1005 (4.7%)
|
0.61
|
0.89
|
|
NCEP, waist >94 cm
|
206/1005 (20.5%)
|
47/1005 (4.7%)
|
0.72
|
0.82
|
B. Incident diabetes
|
Metabolic syndrome
definition
|
Prevalence
of the metabolic syndrome at baseline (n/N,%)
|
Incidence of diabetes
during follow-up (n/N,%)
|
Sensitivity
|
Specificity
|
|
WHO, WHR ³ 0.91
|
211/958 (22.0%)
|
51/958 (5.3%)
|
0.67
|
0.80
|
|
WHO, waist ³ 94 cm
|
180/958 (18.8%)
|
51/958 (5.3%)
|
0.57
|
0.83
|
|
NCEP, waist >102 cm
|
109/958 (11.4%)
|
51/958 (5.3%)
|
0.41
|
0.90
|
|
NCEP, waist >94 cm
|
167/958 (18.0%)
|
51/958 (5.3%)
|
0.49
|
0.84
|
* WHO, World Health Organization. †WHR, waist-hip ratio. ‡NCEP, National
Cholesterol Education Program. Differences in sensitivity of the WHO
definition with WHR >0.90 vs. the WHO definition with waist
³94
cm, at baseline P=0.016, at follow-up, P=0.063; vs NCEP definition
with waist >102 cm, at baseline P=0.006, at follow-up, P<0.001; vs.
NCEP definition with waist >94 cm, at baseline P=0.18, at follow-up,
P=0.022. Differences in specificity of the WHO definition with WHR
>0.90 vs. all other definitions at baseline and follow-up, P<0.001.
Statistical significance was calculated with the McNemar test. In
corresponding analyses with impaired fasting glycemia excluded from
the definitions, sensitivity for especially the NECP definitions was
decreased (WHO definition with waist-hip ratio >0.90 or body-mass
index
³30
kg·m
-2, sensitivity 0.55; WHO definition with waist
³94
cm, sensitivity 0.49; NECP definition with waist >102 cm, sensitivity
0.31; NECP definition with waist >94 cm, sensitivity 0.37), with almost
no effect of specificity [not shown]).