Table 5.Prevalence of the definitions of the metabolic syndrome and their sensitivity and specificity for prevalent (a) and incident (b) cases of diabetes mellitus in middle-aged Finnish men.
A. Prevalent diabetes

Metabolic syndrome

definition

Prevalence of metabolic syndrome (n/N,%)

Prevalence of diabetes (n/N,%)

Sensitivity

Specificity

WHO, WHR ³ 0.91

250/1005 (24.9%)

47/1005 (4.7%)

0.83

0.78

WHO, waist ³ 94 cm

212/1005 (21.1%)

47/1005 (4.7%)

0.68

0.81

NCEP, waist >102 cm

138/1005 (13.7%)

47/1005 (4.7%)

0.61

0.89

NCEP, waist >94 cm

206/1005 (20.5%)

47/1005 (4.7%)

0.72

0.82

B. Incident diabetes

Metabolic syndrome

definition

Prevalence
of the metabolic syndrome at baseline (n/N,%)

Incidence of diabetes

during follow-up (n/N,%)

Sensitivity

Specificity

WHO, WHR ³ 0.91

211/958 (22.0%)

51/958 (5.3%)

0.67

0.80

WHO, waist ³ 94 cm

180/958 (18.8%)

51/958 (5.3%)

0.57

0.83

NCEP, waist >102 cm

109/958 (11.4%)

51/958 (5.3%)

0.41

0.90

NCEP, waist >94 cm

167/958 (18.0%)

51/958 (5.3%)

0.49

0.84

* WHO, World Health Organization. †WHR, waist-hip ratio. ‡NCEP, National Cholesterol Education Program. Differences in sensitivity of the WHO definition with WHR >0.90 vs. the WHO definition with waist ³94 cm, at baseline P=0.016, at follow-up, P=0.063; vs NCEP definition with waist >102 cm, at baseline P=0.006, at follow-up, P<0.001; vs. NCEP definition with waist >94 cm, at baseline P=0.18, at follow-up, P=0.022. Differences in specificity of the WHO definition with WHR >0.90 vs. all other definitions at baseline and follow-up, P<0.001. Statistical significance was calculated with the McNemar test. In corresponding analyses with impaired fasting glycemia excluded from the definitions, sensitivity for especially the NECP definitions was decreased (WHO definition with waist-hip ratio >0.90 or body-mass index ³30 kg·m-2, sensitivity 0.55; WHO definition with waist ³94 cm, sensitivity 0.49; NECP definition with waist >102 cm, sensitivity 0.31; NECP definition with waist >94 cm, sensitivity 0.37), with almost no effect of specificity [not shown]).