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JOURNAL
OF
SPORTS SCIENCE &
MEDICINE
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Research
article
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EFFECTS OF EXERCISE AND CAFFEIC ACID PHENETHYL ESTER AFTER CHRONIC EXERCISE RAT MODEL |
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Ayse Alp1, Sadik Buyukbas2, Harun Alp3  ,
H. Serdar Gergerlioglu4, Mehmet Oz5, M. Kemal Basarali6
and Aysel Kiyici7 |
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1Diyarbakir Training and Research Hospital, Biochemistry Department, Diyarbakir, Turkey, 2Department of Biochemistry, Meram Medical Faculty, Selcuk University, Konya, Turkey, 3Department of Pharmacology and Toxicology, Veterinary Faculty, Dicle University, Diyarbakir, Turkey, 4Department of Physiology, Selcuklu Medical Faculty, Selcuk University, Konya, Turkey, 5Department of Physiology, Selcuk University, Konya, Turkey, 6Department of Biochemistry, Faculty of Medicine, Dicle University, Diyarbakir, Turkey, and 7Department of Biochemistry, Selcuklu Medical Faculty, Selcuk University, Konya, Turkey. |
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© Journal of Sports Science and Medicine (2011) 10, 649 - 654 |
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| ABSTRACT | |||
| In order to understand whether exercise and caffeic acid phenethyl
ester (CAPE) has an effect on obesity and weight control, we investigated
the effects of CAPE, and exercise on lipid parameters (triglyceride, total
cholesterol, HDL-C, LDL-C), and adipokine substances such as leptin and
resistin in rats. 40 male rat were randomly assigned into 4 groups. It was
determined that CAPE does not have any significant effect on these parameters
but that lipid parameters and leptin values in exercise groups decreased
considerably, while no significant change occurred in resistin levels. In
order to understand whether diet has an effect on exercise, body weights
of all animal groups in pre and post-exercise were compared. A significant
weight gain was observed (p = 0.005) in all groups. This study concluded
that exercise has a considerable effect on leptin and lipid parameters;
however, exercise alone was not sufficient for weight control and could
be effective in weight control only when accompanied by a restricted diet. Key words: Caffeic acid phenethyl ester, exercise, leptin, resistin, weight control. |
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