EFFECT OF HOME-BASED WELL-ROUNDED EXERCISE IN COMMUNITY-DWELLING OLDER
ADULTS
|
1Laboratory of Exercise Gerontology, Graduate
School of Natural Sciences, Nagoya City University, Nagoya, Japan
2Center for Physical Activity and Aging, Department of Kinesiology and Sport
Studies, Wichita State University, Wichita, USA
3Department of Family and Community Medicine, University of Kansas School
of Medicine - Wichita, Wichita, USA
| Received |
|
19 September 2005 |
| Accepted |
|
31
October 2005 |
| Published |
|
01
December 2005 |
©
Journal of Sports Science and Medicine (2005) 4, 563
- 571
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| ABSTRACT |
| The
purpose of this study was to assess the efficacy of a home-based well-rounded
exercise program (WREP) in older adults. Forty sedentary community-dwelling
older adults were randomly assigned to an exercise group (n = 23;
aged 62-80 yr, average: 69.2 ± 5.2; 12 men and 11 women) or a control
group (n = 17; aged 63-85 yr, average: 70.1 ± 6.6; 5 men and 12 women).
The exercise group performed a 12-wk WREP which included aerobic exercise
(walking) on about 3 days·wk-1 for 37 min·day-1;
elastic band-based resistance exercises for the major muscle groups
on about 3 days·wk-1 for 26 min; and flexibility exercises
(stretching) on about 4 days·wk-1 for 19 min·day-1.
General physical characteristics, functional strength (Arm Curl [AC],
Chair Stand [CS]), dynamic balance and agility (Up & Go [UG]),
flexibility (Back Scratch [BS], Sit & Reach [SR]), and endurance
(12-min walk [12-MW]) were measured. Following the 12-wk home-based
WREP, improvements were observed in AC, CS, UG, BS, SR and 12-MW for
the exercise group but not for the control group. These results suggest
that the home-based WREP can improve overall fitness in older adults.
KEY
WORDS: Physical fitness, aerobic exercise, resistance exercise,
flexibility exercise, adherence.
|
| INTRODUCTION |
|
It
is estimated that the number of people aged 60 years and over throughout
the world will increase from 606 million in 2000 to 1.9 billion
by 2050 (United Nations, 2003).
Thus, achieving long life and maintaining a high level of physical
activity and vital function is an important challenge for society.
It has been demonstrated that regular exercise is effective for
maintaining and promoting health, physical fitness and functional
independence in older adults, especially in terms of endurance,
muscular strength, flexibility, and balance (American College of
Sports Medicine [ACSM], 1998;
Haskell, 1994;
U.S. Department of Health and Human Services, 1996).
In a recent study, Gill et al. (2004)
found that functional decline and disability can be attenuated,
if not prevented altogether, even in community dwelling frail older
persons by providing home-based semi-supervised exercises called
"prehabilitation".
The ACSM (1998)
suggests the use of a well-rounded exercise program (WREP) for overall
fitness and health. Toraman and Sahin (2004)
reported that supervised multicomponent training including walking,
strengthening and flexibility exercises was effective in improving
various components of functional fitness in younger old adults (aged
60-73 years) as well as older old adults (aged 74-86 years). In
our previous studies, we conducted a WREP which included aerobic,
resistance and flexibility exercises performed in a laboratory setting
with three supervised sessions per week for 12 weeks in healthy
older adults (Takeshima et al., 1999)
and older outpatients (Yamauchi et al., 2003).
The 12-wk supervised training program resulted in significant improvements
in endurance, functional strength, flexibility, agility, serum lipids
and blood pressure.
Unfortunately, in many cases, the benefits of exercise disappear
after cessation of supervised training. Our follow-up survey nine
months after completion of the supervised WREP in healthy older
adults clearly demonstrated that the improvements in many physical
indicators had notably deteriorated (Takeshima, 2002).
In the follow-up study, we inquired about the participants' current
exercise habits after completion of the supervised WREP, focusing
on the type of exercises that they continued to perform. It was
noted that walking was their main mode of exercise during the follow-up
period and they did not perform resistance training. This was principally
attributed to the fact that the training machines used for resistance
exercise in the program were not available at home.
Recently, elastic band-based resistance exercises have become increasingly
popular as an alternative to machine-based resistance exercises.
Reports are available to establish the efficacy of elastic resistance
bands which can be utilized by older adults of various fitness levels
ranging from independently-living older adults (Rogers et al., 2002)
to physically frail community-dwelling older persons (Gill et al.,
2004).
In the late 1980s and early 1990s, home-based exercises (Atienza,
2001;
Brubaker et al., 2000;
Juneau et al., 1987;
King et al., 1991)
and community-based exercises (Hands et al., 1987;
King et al., 1991;
Miller et al., 1984)
were prescribed for middle-aged and healthy older people or patients.
Primarily, aerobic exercises were being prescribed at this point.
Beginning in the mid-1990s, resistance exercises have also been
included (Fatouros et al., 2002;
Gill et al., 2004;
Jette et al., 1996;
King et al., 2000;
Rogers et al., 2002;
Skelton et al., 1995;
Wood et al., 2001).
These conventional studies determined the efficacy of either aerobic,
resistance or flexibility exercise. However, little is known about
the efficacy of a WREP performed in home-based settings. Based on
these concepts and available data, we hypothesized that a home-based
WREP would improve overall functional fitness of community-dwelling
older adults. Thus, the purpose of our study was to evaluate the
efficacy of a 12-week home-based WREP combined with community-based
classes in a group of community-dwelling older adults.
|
| METHODS |
|
Participants
Community-dwelling persons residing in H., Nagoya were recruited
through local Senior Societies and Residents' Associations. Participants
in the study were: (1) sedentary individuals for whom exercise was
not contraindicated for any health reason; and (2) aged 60 and older.
The participants were randomly assigned to one of two groups: the
exercise group or the control group. The exercise group consisted
of 23 participants (aged 62-80 yr, average: 69.2 ± 5.2; 12 men and
11 women). Seven (3 men, 4 women) were taking medication for hypertension,
one woman for diabetes, and two women for osteoporosis. The control
group consisted of 17 participants (aged 63-85 yr, average: 70.1
± 6.6; 5 men and 12 women). The control group originally included
nine men. However, two of these men did not attend the post-assessments,
and two others joined an exercise program, changing their exercise
habits and consequently becoming ineligible for the study. Therefore,
these four men were excluded, resulting in more women than men in
the control group. Seven (4 men, 3 women) were taking medication
for hypertension, and two (1 men, 1 women) for high cholesterol.
General characteristics of the participants are described in Table
1.
Measurement
of general characteristics
After lying supine for five minutes, resting systolic blood pressure
(SBPrest), resting diastolic blood pressure (DBPrest), and resting
heart rate (HRrest) were measured (Table
1) using an automated machine (Colin Stress BP monitor, STBP-680,
Komaki, Japan). Body height and weight were measured using a TANITA
body fat analyzer TBF-202 (Tanita Co., Tokyo, Japan). Body mass
index (BMI) was computed as body weight (kg) divided by the square
of height (m). The participants were asked to assess their health
as good, average or poor.
Measurement of functional fitness
Upper body functional strength was assessed using the 30-second
Arm Curl Test [AC] (Rikli and Jones, 1999b).
On a signal, participants were instructed to flex and extend the
elbow of the dominant hand, lifting a weight (men: 8-pound dumbbell,
women: 5-pound dumbbell) through the complete range of motion, as
many times as possible in 30 seconds. After a demonstration by the
tester, a practice trial of one or two repetitions was given, followed
by one 30-s test trial. The score was the number of repetitions
completed within 30 seconds.
Lower body functional strength was assessed using the 30-second
Chair Stand Test [CS] (Rikli and Jones, 1999a).
On a signal, participants rose to a full standing position from
a chair and then returned to a fully seated position, and continued
to complete as many full stands as possible in 30 seconds. After
a demonstration by the tester, a practice trial of one to three
repetitions was given, followed by one 30-s test trial. The score
was the total number of stands executed correctly within 30 seconds.
Dynamic balance and Agility was assessed using the 8-foot Up and
Go Test [UG] (Rikli and Jones, 1999a).
Participants fully seated in a chair, hands on thighs and feet flat
on the floor. On a signal, participants stood from the chair, walked
as quickly as possible around a cone which was placed 8 feet (2.44
m) ahead of the chair, and returned to a fully seated position on
the chair. Participants were told that this is a timed test and
that the object was to walk as quickly as possible (without running)
around the cone and back to the chair. After a demonstration by
the tester, participants were given one practice trial and two test
trials. The best performance time of the test trials was recorded
in units of 0.1 second.
Upper body flexibility was assessed using the Back Scratch Test
[BS] (Rikli and Jones, 1999a).
Participants placed the preferred hand behind the same side shoulder
with the forearm pronated and fingers extended. They placed the
other hand behind the back, forearm supinated, reaching up in an
attempt to touch or overlap the extended middle fingers of both
hands. After a demonstration by the tester, participants were asked
to determine the preferred hand, and were given two practice trials,
followed by two test trials. The score was the number of centimeters
the middle fingers were short of touching (minus score) or overlapped
each other (plus score). The best score of test trials was used
to evaluate performance.
Lower body flexibility was assessed using the Chair Sit and Reach
Test [SR] (Rikli and Jones, 1999a).
Participants sat on the edge of a chair with one leg bent and the
other leg extended straight in front with the heel on the floor.
Without bending the knee, participants slowly reached forward, sliding
the hands down the extended leg in an attempt to touch the toes.
After a demonstration by the tester, participants were asked to
determine the preferred leg and were given two practice trials on
that leg, followed by two test trials. The score was the number
of centimeters short of reaching the toes (minus score) or reached
beyond the toes (plus score). The best score of two test trials
was used to evaluate performance.
Endurance was assessed by performing the 12-minute Walk Test [12-MW]
(Takeshima et al., 1992).
The 12-minute Walk Test involved assessing the maximum distance
walked in 12 minutes around a 60-meter rectangular course marked
into 5-meter segments. The score was the total number of meters
walked in 12 minutes.
Exercise program
The home-based exercise program consisted of flexibility, resistance
and aerobic exercises. Participants were instructed to perform exercises
at least three times a week in addition to the weekly supervised
exercise class. They were advised to choose the mode of exercise
for each home- based session based on the weekly supervised exercise
class. A pictorial guidebook and a videotape were provided to each
participant to assist them in correct exercise performance. The
pictorial guidebook and the videotape were developed by the researchers
using trained fitness instructors and older adults as models.
Flexibility
exercise (stretching)
Participants were asked to perform several types of stretching each
time from eight types of upper body exercises and seven types of
lower body exercises described in the guidebook. These exercises
were performed as warm up and cool down activities before and after
performing aerobic or resistance exercises. Exercises were performed
slowly, holding each position for approximately 10 to 12 seconds.
Participants were instructed to stretch to a point of moderate tension
without pain in the joints or muscles, gradually increasing the
range of motion.
Elastic band-based resistance exercise
In order to train all major muscle groups, resistance exercises
were prescribed as a combination of eight upper body exercises and
nine lower body exercises performed in the seated position using
an elastic resistance band (Thera-Band®, Hygenic, USA).
Participants were instructed to progressively increase resistance
every two to four weeks by advancing to the next color of elastic
band (lower to higher resistance of bands in order: tan, yellow,
red, green, blue, black, silver and gold). Specifically, participants
were instructed to change bands when they were able to perform 20
repetitions of a given motion with little exertion. Exertion was
rated using Borg's Rate of Perceived Exertion (RPE) scale (Borg,
1982).
Participants were instructed to start resistance exercises at an
intensity level of 11 to 13 of Borg's RPE scale and then to progressively
increase to a level of 15 to 17. However, actual setting of resistance
was very subjective. Participants were instructed to not hold their
breath during the exercises in order to prevent exercise-induced
blood pressure elevations.
Aerobic exercise (walking)
Participants were instructed to walk regularly around their home
and parks near the community center as much as possible. Participants
were instructed to walk at an intensity corresponding to a heart
rate of 100-120 bpm. Maximal heart rate (HRmax) was not measured
directly, however, in a previous study we found that a HR of 100-120
bpm represented an intensity of 70% to 80% of HRmax for people aged
approximately 70 years (Takeshima et al., 1993).
In the community-based maintenance exercise class, each participant
wore a heart rate monitoring device (Accurex Plus, Polar Electro,
Kempele, Finland) that each participant wore a heart rate monitoring
device (Accurex Plus, Polar Electro, Kempele, Finland) that continuously
monitored his or her HR during the class. Participants were asked
to walk at speeds that represented their regular walking exercise
speeds, and were informed of their recorded heart rate. Advice was
given to those needing to increase or decrease exercise intensity
to maintain the prescribed intensity.
Exercise
classes at a community center
Maintenance exercise classes were held once a week at a local community
center to provide participants with instruction regarding correct
exercise techniques. These sessions were conducted by trained exercise
instructors and supervised by the researchers. Each maintenance
class consisted of general warm-up exercises (10min), elastic band-based
resistance exercise (40 min) or walking- based aerobic exercise
(40 min), and cool-down/relaxation exercises (10 min). Adherence
rate was calculated as the number of maintenance classes attended
divided by the number of total maintenance classes.
To determine actual implementation of home-based exercise, participants
were asked to submit a diary every week when attending the exercise
classes. Participants were asked to record exercises performed with
regard to body part exercised as well as the type, frequency, duration
and intensity of exercise.
Data processing
The data are expressed as mean ± standard deviation. The effect
of the intervention was determined using a 2-way ANOVA with repeated
measures. Between group mean baseline comparisons were performed
using a two-tailed, independent t-test. To determine relationships
between variables, Pearson product-moment correlation analyses were
calculated. A P value, set a priori, of less than 0.05 was considered
statistically significant.
|
| RESULTS |
|
No
differences were found between the exercise group and the control
group before the intervention in terms of age, weight, height, BMI,
SBPrest, DBPrest, and HRrest (Table
1). As for the participants' self-assessed health condition,
14 participants (61%) in the exercise group and 9 participants (59%)
in the control group reported that they were in good condition (Table
1). Ten participants (44%) in the exercise group and 9 participants
(53%) in the control group were taking medication. Approximately
85% of the participants had completed secondary education. No differences
were observed between the two groups in terms of self-assessed health
condition or educational background (Table
1). Before the intervention, there were no significant differences
between the groups for AC, CS, UG, BS, SR or 12-MW, however, after
the 12-wk intervention significant group interactions as well as
time effects were observed for all functional fitness scores (Table
2).
Frequency
and duration of exercise
The exercise group performed home-based exercises (in addition to
the maintenance classes) on 4.3 ± 1.3 days·week-1. Average
total exercise duration was 248 ± 107 min·week-1. Flexibility
exercise was performed on 3.9 ± 1.7 days·week-1 with
an average exercise duration of 19 ± 4 min/day. Resistance exercise
was performed on 3.0 ± 1.5 days·week-1 with an average
exercise duration of 26 ± 7 min·day-1 and an average
RPE of 12.7 ± 0.8. With respect to beginning levels of elastic band
resistance (band resistance - lower to higher: tan, yellow, red,
green, blue, black, silver and gold), 6 of 11 women (55%) chose
yellow and 5 women (46%) chose red. Among 12 men, 7 men (58%) chose
red, 3 men (25%) chose green, and 2 men (17%) chose blue. At the
end of the intervention, 1 woman (9%) used yellow, 9 women (82%)
used red, 1 woman (9%) used green; 4 men (33%) used red, 5 men (42%)
used green, and 3 men (25%) used blue. These observations indicate
that the participants progressively increased the level of resistance,
and therefore exercise intensity, during the intervention. Aerobic
exercise was performed on 2.5 ± 1.4 days·week-1, with
an average exercise duration of 37 ± 21 min and an average RPE of
12.3 ± 0.8 (Table 3).
Adherence
and exercise duration
The average adherence rate in the exercise class at the community
center was 83 ± 11%. Significant correlations were observed between
adherence rate and total time spent engaging in the home-based exercise
program (average = 248 ± 107 min·week-1, r = 0.73, p
< 0.05). There were no accidents or injuries during the exercise
classes at the community center or at home. All participants in
the exercise group completed the entire 12-week home-based exercise
program.
|
| DISCUSSION |
|
A well-rounded
exercise program (WREP) is considered to be an effective exercise
program for attenuating deterioration in functional fitness associated
with aging and a sedentary lifestyle. Wood et al. (2001)
conducted programs for older adults which included cardiovascular
training (CVT), resistance training (RT) or both CVT and RT. They
concluded that the program incorporating both CVT and RT is more
effective in improving functional fitness than the programs involving
only one component. Barnett et al. (2003)
recruited elderly subjects who were at risk of falling. They prescribed
a program including aerobic, flexibility and resistance exercises,
and found improvements in balance and a decrease in the prevalence
of falls. Rogers et al. (2002)
provided African-American elderly women with community-based exercise
classes using elastic resistance bands and observed improvements
in upper and lower body strength. Aniansson et al. (1984)
studied elderly women and prescribed resistance exercise sessions
using elastic bands and found increases in muscle strength. Jette
and colleagues (1996;
1998;
1999)
examined resistance training with elastic bands in several studies
and concluded that balance and functional fitness as well as muscle
strength improved. The present study examined a home-based WREP
in Japanese older adults. We found the program to be effective for
improving endurance, functional strength, agility and flexibility.
However, additional research is needed to determine the specific
types and amount of exercise that should be performed to provide
optimal fitness benefits.
In this study, elastic bands were used for resistance training because
they are simple, portable and inexpensive tools. They do not require
large storage space or special facilities, and can be easily used
for both community- and home-based exercises (Gill et al., 2004).
Eight to ten types of exercises were introduced for the upper and
lower body, and each motion was to be repeated 10-12 times (Feigenbaum
and Pollock, 1997).
As a result, we observed improvement in the AC and CS. Furthermore,
the UG also improved in the exercise group. Other studies support
the effectiveness of elastic bands as resistance exercise (Barnett
et al., 2003;
King et al., 2000;
Rogers et al., 2002).
In the current study, participants were encouraged to walk for aerobic
exercise. Participants were instructed to maintain prescribed exercise
intensity by monitoring their pulse. They walked an average of 2.5
days·week-1 for 37 min·day-1. As a result,
endurance of the exercise group as measured by the 12-MW improved
significantly. However, some challenges still remain for prescribing
home-based aerobic exercises. Outdoor exercises can be interrupted
by inclement weather, while the housing situation often does not
allow enough space for placing a treadmill or a stationary bike
in the homes of older adults.
Joint range-of-motion deteriorates in accordance with age, especially
in sedentary older adults. This can lead to difficulty in performing
daily living activities such as bathing and dressing, and can contribute
to falls that cause injuries (Barnett et al., 2003).
Furthermore, the decline in lower body flexibility can negatively
affect walking speed. Campanelli (1996)
reported that the age-related changes in flexibility are largely
related to declines in physical activity, though the degree of deterioration
differs among individuals. Fatouros et al. (2002)
examined inactive older adults, performing 16 weeks of aerobic and
resistance exercise, and observed remarkable improvement in joint
range of motion. We measured flexibility of upper and lower body
using Back Scratch and Sit & Reach tests which have been validated
by Rikili and Jones (1999a)
and adopted in other studies (Marzilli et al., 2004;
Toraman and Sahin, 2004).
Our study observed significant increases in flexibility in BS and
SR in exercise group. Although BS scores of the control group showed
decrease by 2.2cm, it should be noted that the scores of three control
participants were deemed outliers due to an extremely large decrease
in post-intervention BS scores showing mean change of -9.8 cm within
these three people. Mean change excluding these three people was
-0.6 cm. These three participants experienced a shoulder joint injury
resulting in poor post-intervention performance. Their injuries
were not related to the exercise program itself. A small stimulus
such as carrying groceries or carrying a shoulder bag could have
caused upper body muscle pain or shoulder joint pain in these people,
and it may have affected their BS performance. Unfortunately, no
effort was made to study specific shoulder joint pain during pre
and post tests in this study. However, the noted improvements in
the exercise group may help these individuals to live independently
for longer periods of time and to continue to perform activities
such as combing hair, dressing and undressing.
Motivating older adults to perform exercises on a regular basis
is an important factor in achieving high adherence rates and maintaining
the effects of exercise. Data from Martin and Sinden (2001)
suggest that occasional direct contact with the participants via
telephone, internet or personal visit increases adherence to home
exercise programs among older adults. In our previous study, we
provided supervised exercise classes three days a week for 12 weeks
for older adults (Yamauchi et al., 2003).
The adherence rate was 94% and most participants mentioned that
they were glad to make new friends and enjoyed exercising as a group.
This suggests that community-based exercise classes in a group setting
have positive psychological effects as well as physical effects.
In the current study, we held community-based exercise classes once
a week in addition to the home-based exercise program. The adherence
rate to the community-based classes was 83%, and a positive correlation
was observed between the adherence rate and the performance of home-based
exercise. These facts suggest that the community-based exercise
classes promoted exchanges among the participants, and successfully
developed incentives for exercise participation. After completion
of this 12-week program, participants continued to exercise and
currently attend exercise classes twice a month with the aim of
observing fitness changes that may occur over an extended period
of time.
To evaluate exercise effects, we used a functional fitness test
battery that was originally developed and validated by Rikli and
Jones (1999a)
of the United States. This battery can be easily performed by older
adults and normative scores for the tests are available (Rikli and
Jones, 1999b).
The participants in the present study showed better test scores
in almost all the variables compared to their age-matched normative
scores. This may suggest that Japanese people demonstrate greater
functional fitness than age-matched American people. Two previous
studies have yielded similar findings. Both Davis et al. (1999)
and Loy et al. (2001)
report better functional fitness scores in older Japanese persons
compared to Caucasian subjects. Rationale to explain the higher
functional fitness levels of Japanese subjects has yet to be determined,
however, it is possibly related to genetic and cultural factors.
For example, squatting to toilet or getting up from the floor, which
are commonly performed in Japanese daily life, may help maintain
lower body functional strength, while going shopping on foot and
carrying groceries by hand may also be helpful in maintaining muscular
strength. However, little information is provided regarding Asian
racial groups in the literature (Atienza, 2001)
posing a need for future research.
|
| CONCLUSIONS |
| A
WREP has been shown to improve overall fitness in older adults. By
combining aerobic, resistance and flexibility exercises, a WREP was
effective for improving endurance, functional strength, dynamic balance
and agility, and flexibility. Furthermore, a high correlation was
observed between adherence rate of community-based exercise classes
and performance of home-based exercise, indicating that community-based
exercise promotes participation in home-based exercise. |
| ACKNOWLEDGEMENTS |
| The
authors acknowledge the participants for their voluntary involvement
in this study. This study was supported by Ministry of Education,
Culture, Sports, Science and Technology (Japan), The Univers, and
Hygenic Corporation grants. |
| KEY
POINTS |
- Walking,
elastic band exercise and stretching were prescribed as a Well-Rounded
Exercise Program for older adults.
- By
combining aerobic, resistance and flexibility exercises, a Well-Rounded
Exercise Program was effective for improving endurance, functional
strength, dynamic balance and agility, and flexibility.
- Community-based
exercise classes motivated older adults to perform home-based
exercises.
|
| AUTHORS
BIOGRAPHY |
Tomoko YAMAUCHI
Employment: Laboratory of Exercise Gerontology, Graduate
School of Natural Sciences, Nagoya City University, Nagoya,
Japan
Degree: PhD.
Research interests: Health promotion for older adults.
E-mail: t.yamauchi@nsc.nagoya-cu.ac.jp |
|
Mohammod M. ISLAM
Employment: Laboratory of Exercise Gerontology, Graduate
School of Natural Sciences, Nagoya City University, Nagoya,
Japan.
Degree: PhD.
Research interests: Fall prevention in older adults.
E-mail: m.islam@nsc.nagoya-cu.ac.jp |
|
Daisuke KOIZUMI
Employment: Laboratory of Exercise Gerontology, Graduate
School of Natural Sciences, Nagoya City University, Nagoya,
Japan.
Degree: MSc.
Research interests: Physical activity assessment for
older adults.
E-mail: d.koizum@nsc.nagoya-cu.ac.jp |
|
Michael
E. ROGERS
Employment: Center for Physical Activity and Aging, Department
of Kinesiology and Sport Studies, Wichita State University,
Wichita, USA
Degree: PhD.
Research interests: Strength and balance training programs
for older adults.
E-mail: michael.rogers@wichita.edu |
|
Nicole L. ROGERS
Employment: Department of Family and Community Medicine,
University of Kansas School of Medicine - Wichita, Wichita,
USA
Degree: PhD.
Research interests: Health promotion for older adults.
E-mail: nrogers2@kumc.edu |
|
Nobuo TAKESHIMA
Employment: Laboratory of Exercise Gerontology, Graduate
School of Natural Sciences, Nagoya City University, Nagoya,
Japan
Degree: PhD.
Research interests: Well-rounded exercise program for
older adults.
E-mail: nob@nsc.nagoya-cu.ac.jp |
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