Abrams, J. (2003) C-reactive protein, inflammation, and coronary risk: An update. Cardiology Clinics 21, 327-331.

Åstrand, P.O. (1988) Work tests with the bicycle ergometer. Monark Crescent AB, Varberg.

Bassuk, S.S. and Manson, J.E. (2003) Physical activity and the prevention of cardiovascular disease. Current Atherosclerosis Reports 5, 299-307.

Bots, M.L., Hoes, A.W., Koudstaal, P.J., Hofman, A. and Grobbee, D.E. (1997) Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam Study. Circulation 96, 1432-1437.

Carroll, S., Cooke, C.B. and Butterly, R.J. (2000) Leisure time physical activity, cardiorespiratory fitness, and plasma fibrinogen concentrations in nonsmoking middle-aged men. Medicine Science in Sports and Exercise 32, 620-626.

Clauss, A. (1957) Rapid physiological coagulation method for the determination of fibrinogen. Acta Haematologica 17, 237-246.

Celermajer, D.S., Sorensen, K.E., Gooch, V.M., Spiegelhalter, D.J., Miller, O.I., Sullivan, I.D., Lloyd, J.K. and Deanfield, J.E. (1992) Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 340, 1111-1115.

Chandra, H.R., Goldstein, J.A., Choudhary, N., O'Neill, C.S., George, P.B., Gangasani, S.R., Cronin, L., Marcovitz, P.A., Hauser, A.M. and O'Neill, W.W. (2004) Adverse outcome in aortic sclerosis is associated with coronary artery disease and inflammation. Journal of the American College of Cardiology 43, 169-175.

Danesh, J., Collins, R., Appleby, P. and Peto, R. (1998) Association of fibrinogen, C reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies. The Journal of the American Medical Association 279, 1477-1482.

De Keulenaer, G.W., Chappell, D.C., Ishizaka, N., Nerem, R.M., Alexander, R.W. and Griendling, K.K. (1998) Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide producing NADH oxidase. Circulation Research 82, 1094-1101.

DeSouza, C.A., Shapiro, L.F., Clevenger, C.M., Dinenno F.A., Monahan, K.D., Tanaka, H. and Seals, D.R. (2000) Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilatation in healthy men. Circulation 120, 1351-1357.

Dimmeler, S., Hermann, C., Galle, J. and Zeiher, A.M. (1999) Upregulation of superoxide dismutase and nitric oxide synthase mediates the apoptosis suppressive effects of shear stress on endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology 19, 656-664.

Elosua, R., Bartali, B., Ordovas, J.M., Corsi, A.M., Lauretani, F. and Ferrucci, L. (2005) Association between physical activity, physical performance, and inflammatory biomarkers in an elderly population: the InCHIANTI study. Journals of Gerontology: Biological and Medical Sciences 60, 760-767.

Elwood, P.C., Yarnell, J.W.G., Pickering, J., Fehily, A.M. and O'Brien, J.R. (1993) Exercise, fibrinogen and other risk factors for ischemic heart disease. Caerphilly Prospective Heart Disease Study. British Heart Journal 69, 183-187.

Folsom, A.R., Wu, K.K., Davis, C.E., Conlan, M.G., Sorlie, P.D. and Szklo, M. (1991) Population correlates of plasma fibrinogen and factor VII, putative cardiovascular risk factors. Atherosclerosis 91, 191-205

Friedewald, W.T., Levy, R.J. and Fredrickson, D.S. (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clinical Chemistry 18, 499-502.

Geffken, D.F., Cushman, M., Burke, G.L., Polak, J.F., Sakkinen, P.A. and Tracy, R.P. (2001) Association between physical activity and markers of inflammation in a healthy elderly population. American Journal of Epidemiology 153, 242-250.

Gibbons, L. and Clark, M. (2001) Exercise in the reduction of cardiovascular events. Exercise in secondary prevention and cardiac rehabilitation. Cardiology Clinics 19, 347-355.

Gielen, S. and Hambrecht, R. (2001) Effects of exercise training on vascular function and myocardial perfusion. Exercise in secondary prevention and cardiac rehabilitation. Cardiology Clinics 19, 357-368.

Hagg, U., Wandt, B., Bergstrom, G., Volkmann, R. and Gan, L.M. (2005) Physical exercise capacity is associated with coronary and peripheral vascular function in healthy young adults.

American Journal of Physiology, Heart and Circulatory Physiology 289, 1627-1634.

Higashi, Y., Sasaki, S., Kurisu, S., Yoshimizu, A., Sasaki, N., Matsuura, H., Kajiyama, G. and Oshima, T. (1999) Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects: role of endothelium-derived nitric oxide. Circulation 100, 1194-1202.

Horne, B.D., Anderson, J.L., John, J.M., Weaver, A., Bair, T.L., Jensen, K.R., Renlund, D.G. and Muhlestein, J.B. (2005) Which white blood cell subtypes predict increased cardiovascular risk? Journal of the American College of Cardiology 45, 1638-1643.

Hornig, B., Maier, V. and Drexler, H. (1996) Physical training improves endothelial function in patients with chronic heart failure. Circulation 93, 210-214.

Johansson, S.E. and Sundquist, J. (1999) Change in lifestyle factors and their influence on health status and all-cause mortality. International Journal of Epidemiology 28, 1073-1080.

Kritchevsky, S.B., Cesari, M. and Pahor, M. (2005) Inflammatory markers and cardiovascular health in older adults. Cardiovascular Research 66, 265-275.

Kuvin, J.T., Patel, A.R., Sliney, K.A., Pandian, N.G., Rand, W.M., Udelson, J.E. and Karas R.H. (2001) Peripheral vascular endothelial function testing as a noninvasive indicator of coronary artery disease. Journal of the American College of Cardiology 38, 1843-1849.

Lakka, T.A., Laukkanen, J.A., Rauramaa, R., Salonen, R., Lakka, H.M., Kaplan, G.A. and Salonen, J.T. (2001) Cardiorespiratory fitness and the progression of carotid atherosclerosis in middle-aged men. Annals of Internal Medicine 134, 12-20.

Lakka, T.A. and Salonen, J.T. (1993) Moderate to high intensity conditioning leisure-time physical activity and high cardiorespiratory fitness are associated with reduced plasma fibrinogen in eastern Finnish men. Journal of Clinical Epidemiology 46, 1119-1127.

Leon, A.S. and Sanchez, O.A. (2001) Response of blood lipids to exercise training alone or combined with dietary intervention. Medicine Science in Sports and Exercise 33(6 Suppl): 502-515.

Macy, E., Hayes, T. and Tracy, R. (1997) Variability in the measurement of C-reactive protein in healthy subjects: implications for reference intervals and epidemiological applications. Clinical Chemistry 43, 52-58.

Maiorana, A., O'Driscoll, G., Cheetham, C., Dembo, L., Stanton, K., Goodman, C., Taylor, R. and Green, D. (2001) The effect of combined aerobic and resistance exercise training on vascular function in type 2 diabetes. Journal of the American College of Cardiology 38, 860-866.

Markus, R.A., Mack, W.J., Azen, S.P. and Hodis, H.N. (1997) Influence of lifestyle modification on atherosclerotic progression determined by ultrasonographic change in the common carotid intima-media thickness. American Journal of Clinical Nutrition 65, 1000-1004.

Marsh, S.A. and Coombes, J.S. (2005) Exercise and the endothelial cell. International Journal of Cardiology 99, 165-169.

Morris, C.K. and Froeclicher, V.F. (1993) Cardiovascular benefits of improved exercise capacity. Sports Medicine 16, 225-236.

Munro, J. and Cotran, R. (1988) The pathogenesis of atherosclerosis: atherogenesis and inflammation. Laboratory Investigation 58, 249-261.

Myers, J., Prakash, M., Froelicher, V., Do, D., Partington, S. and Atwood, J.E. (2002) Exercise capacity and mortality among men referred for exercise testing. New England Journal of Medicine 346, 793-801.

O'Leary, D.H., Polak, J.F., Kronmal, R.A., Manolio, T.A., Burke, G.L. and Wolfson, S.K. (1999) Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. New England Journal of Medicine 340, 14-22.

Paffenbarger, R.S., Hyde, R.T., Wing, A.L., Lee, I.M., Jung, D.L. and Kampert, J.B. (1993) The association of changes in physical activity level and other lifestyle characteristics with mortality among men. New England Journal of Medicine 328, 538-545.

Palmieri, E.A., Palmieri, V., Innelli, P., Arezzi, E., Ferrara, L.A., Celentano, A., and Fazio, S. (2005) Aerobic exercise performance correlates with post-ischemic flow-mediated dilation of the brachial artery in young healthy men. European Journal of Applied Physiology 94, 113-117.

Rauramaa, R., Rankinen, T., Tuomainen, P., Vaisanen, S. and Mercuri, M. (1995) Inverse relationship between cardiorespiratory fitness and carotid atherosclerosis. Atherosclerosis 112, 213-221.

Reidy, M.A. and Langille, B.L. (1980) The effect of local blood flow patterns on endothelial cell morphology. Experimental and Molecular Pathology 32, 276-289.

Ridker, P.M., Rifai, N., Rose, L., Buring, J.E. and Cook, N.R. (2002) Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. New England Journal of Medicine 347, 1557-1565.

Rosengren, A. and Wilhelmsen, L. (1997) Physical activity protects against coronary death and deaths from all causes in middle-aged men. Evidence from a 20-year follow-up of the primary prevention study in Goteborg. Annals of Epidemiology 7, 69-75.

Rosenson, R.S. and Koenig, W. (2003) Utility of inflammatory markers in the management of coronary artery disease. American Journal of Cardiology 92, 10i-18i.

Ross, R. (1993) The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362, 801-809.

Ross, R. (1999) Atherosclerosis-an inflammatory disease. New England Journal of Medicine 340, 115-126.

Saltin, B. (1969) Physiological effects of physical conditioning. Medicine Science in Sports and Exercise 1, 50-56.

Sinha, A.K., Eigenbrodt, M. and Mehta, J.L. (2002) Does carotid intima media thickness indicate coronary atherosclerosis? Current Opinion in Cardiology 17, 526-530.

Stratton, J.R., Chandler, W.L., Schwartz, R.S., Cerqueira, M.D., Levy, W.C., Kahn, S.E., Larson, V.G., Cain, K.C., Beard, J.C. and Abrass, I.B. (1991) Effects of physical conditioning on fibrinolytic variables and fibrinogen in young and old healthy adults. Circulation 83, 1692-1697.

Taddei, S., Galetta, F., Virdis, A., Ghiadoni, L., Salvetti, G., Franzoni, F., Giusti, C. and Salvetti, A. (2000) Physical activity prevents age-related impairment in nitric oxide availability in elderly athletes. Circulation 101, 2896-2901.

Takeshita, S., Inoue, N., Ueyama, T., Kawashima, S. and Yokoyama, M. (2000) Shear stress enhances glutathione peroxidase expression in endothelial cells. Biochemical and Biophysical Research Communications 273, 66-71.

Targher, G., Seidell, J.C., Tonoli, M., Muggeo, M., De Sandre, G. and Cigolini, M. (1996) The white blood cell count: its relationship to plasma insulin and other cardiovascular risk factors in healthy male individuals. Journal of Internal Medicine 239, 435-451.

Thompson, P.D., Buchner, D., Pina, I.L., Balady, G.J., Williams, M.A., Marcus, B.H., Berra, K., Blair, S.N., Costa, F., Franklin, B., Fletcher, G.F., Gordon, N.F., Pate, R.R., Rodriguez, B.L., Yancey, A.K. and Wenger, N.K. (2003) Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease. Circulation 107, 3109-3116.

Tracy, R. (1997) Atherosclerosis, thrombosis and inflammation: a problem of linkage. Fibrinolysis 11, 1-5.

Verdaet, D., Dendale, P., De Bacquer, D., Delanghe, J., Block, P. and De Backer, G. (2004) Association between leisure time physical activity and markers of chronic inflammation related to coronary heart disease. Atherosclerosis 176, 303-310.

Wannamethee, S.G., Shaper, A.G. and Walker, M. (1998) Changes in physical activity, mortality and incidence of coronary heart disease in older men. Lancet 30, 1603-1608.

Wilmore, J.H. and Benkhe, A.R. (1969) An anthropometric estimation of body density and lean body weight in young man. Journal of Applied Physiology 27, 25-31.

WMADH (2000) World Medical Association Declaration of Helsinki. The Journal of the American Medical Association 20, 3043-3045.

Wolfe, L.A., Martin, R.P., Watson, D.D., Lasley, R.D. and Bruns, D.E. (1985) Chronic exercise and left ventricular structure and function in healthy human subjects. Journal of Applied Physiology 58, 409-415.

Yu, S., Yarnell, J.W., Sweetnam, P.M. and Murray, L. (2003) What level of physical activity protects against premature cardiovascular death? The Caerphilly study. Heart 89, 502-506.