Allen, D.L., Harrison, B.C., Maass, A., Bell, M.L., Byrnes, W.C. and Leinwand, L.A. (2001) Cardiac and skeletal muscle adaptations to voluntary wheel running in the mouse. Journal of Applied Physiology 90, 1900-1908.

Andrianopoulos, G., Nelson, R.L., Bombeck, C.T. and Souza, G. (1987) The influence of physical activity in 1,2 dimethylhydrazine induced colon carcinogenesis in the rat. Anticancer Research 7, 849-852.

Anthony, T.G., Anthony, J.C., Lewitt, M.S., Donovan, S.M. and Layman, D.K. (2001) Time course changes in IGFBP-1 after treadmill exercise and postexercise food intake in rats. American Journal of Physiology, Endocrinology and Metabolism 280, E650-656.

Bang, P., Brandt, J., Degerblad, M., Enberg, G., Kaijser, L., Thoren, M. and Hall, K. (1990) Exercise-induced changes in insulin-like growth factors and their low molecular weight binding protein in healthy subjects and patients with growth hormone deficiency. European Journal of Clinical Investigation 20, 285-292.

Banu, M.J., Orhii, P.B., Mejia, W., McCarter, R.J., Mosekilde, L., Thomsen, J.S. and Kalu, D.N. (1999) Analysis of the effects of growth hormone, voluntary exercise, and food restriction on diaphyseal bone in female F344 rats. Bone 25, 469-480.

Barnard, R.J., Ngo, T.H., Leung, P.-S., Aronson, W.J. and Golding, L.A. (2003) A low fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate tumor cell growth in vitro. Prostate 56, 201-206.

Bravenboer, N., Engelbregt, M.J., Visser, N.A., Popp-Snijders, C. and Lips, P. (2001) The effect of exercise on systemic and bone concentrations of growths factors in rats. Journal of Orthopaedic Research 19, 945-949.

Buehlmeyer, K., Doering, F., Daniel, H., Schulz, T. and Michna, H. (2007) Exercise associated genes in rat colon mucosa: upregulation of ornithin decarboxylase-1. International Journal of Sports Medicine 28, 361-367.

Chadan, S.G., Dill, R.P., Vanderhoek, K. and Parkhouse, W.S. (1999) Influence of physical activity on plasma insulin-like growth factor-1 and insulin-like growth factor binding proteins in healthy older women. Mechanisms of Ageing and Development 109, 21-34.

Colbert, L. H., Davis, J. M., Essig, D. A., Ghaffar, A. and Mayer, E. P. (2000) Exercise and tumor development in a mouse predisposed to multiple intestinal adenomas Medicine Science and Sports Exercise, 32, 1704-8.

Colbert, L.H., Mai, V., Perkins, S.N., Berrigan, D., Lavigne, J.A., Wimbrow, H.H., Alvord, W.G., Haines, D.C., Srinivas, P. and Hursting, S.D. (2003) Exercise and intestinal polyp development in APCMin mice. Medicine Science and Sports Exercise 35, 1662-1669.

Colditz, G.A., Cannuscio, C.C. and Frazier, A.L. (1997) Physical activity and reduced risk of colon cancer: implications for prevention. Cancer Causes Control 8, 649-667.

Cooper, D.M., Moromisato, D., Zanconato, S., Moromisato, M., Jensen, S. and Brasel, J.A. (1994) Effect of growth hormone suppression on exercise training and growth response in young rats. Pediatric Research 35, 223-227.

Demarzo, M.M. and Garcia, S.B. (2004) Exhaustive physical exercise increases the number of colonic preneoplastic lesions in untrained rats treated with a chemical carcinogen. Cancer Letters 216, 31-34.

Eliakim, A., Moromisato, M., Moromisato, D., Brasel, J.A., Roberts, C. and Cooper, D.M. (1997) Increase in muscle IGF-I protein but not IGF-I mRNA after 5 days of endurance training in young rats. American Journal of Physiology 42, 1557-1561.

Friedenreich, C.M. and Orenstein, M.R. (2002) Physical activity and cancer prevention: etiologic evidence and biological mechanisms Journal of Nutrition 132, 3456S-3464S.

Giovannucci, E. (2001) Insulin, insulin-like growth factors and colon cancer: A review of the evidence. Journal of Nutrition 131, 3109-3120.

Grimberg, A. and Cohen, P. (2000) Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis. Journal of Cell Physiology 183, 1-9.

Gunter, M.J. and Leitzmann, M.F. (2005) Obesity and colorectal cancer: epidemiology, mechanisms and candidate genes. Journal of Nutritional Biochemistry 17, 145-156.

Jemiolo, B. and Trappe, S. (2004) Single muscle fiber gene expression in human skeletal muscle: validation of internal control with exercise. Biochemical and Biophysical Research Communication 320, 1043-1050.

Kaaks, R. and Lukanova, A. (2002) Effects of weight control and physical activity in cancer prevention: role of endogenous hormone metabolism. Annals of the New York Academy of Sciences 963, 268-281.

Kingwell, B.A., Arnold, P.J., Jennings, G.L. and Dart, A.M. (1998) The effects of voluntary running on caridac mass and aortic compliance in Wistar-Kyoto and spontaneously hypertensive rats. Journal of Hypertension 16, 181-185.

Koistinen, H., Koistinen, R., Selenius, L., Ylikorkala, Q. and Seppala, M. (1996) Effect of marathon run on serum IGF-I and IGF-binding protein 1 and 3 levels. Journal of Applied Physiology 80, 760-764.

Kostka, T., Patricot, M.C., Mathian, B., Lacour, J.R. and Bonnefoy, M. (2003) Anabolic and catabolic hormonal responses to experimental two-set low-volume resistance exercise in sedentary and active elderly people. Aging Clinical and Experimental Research 15, 123-130.

Kraemer, R.R., Durand, R.J., Acevedo, E.O., Johnson, L.G., Kraemer, G.R., Hebert, E.P. and Castracane, V.D. (2004) Rigorous running increases growth hormone and insulin-like growth factor-I without altering grehlin. Experimental Biology and Medicine 229, 240-246.

Kritchevsky, D. (1999) Caloric Restriction and Experimental Carcinogenesis. Toxicological Sciences, 52, 13-16.

Leung, P.-S., Aronson, W.J., Ngo, T.H., Golding, L.A. and Barnard, R.J. (2003) Exercise alters the IGF axis in vivo and increases p53 protein in prostate tumor cells in vitro. Journal of Applied Physiology 96, 450-454.

Mahoney, D.J., Carey, K., Fu, M.H., Snow, R., Cameron-Smith, D., Parise, G. and Tarnopolsky, M.A. (2004) Real-time RT-PCR analysis of housekeeping genes in human skeletal muscle following acute exercise. Physiological Genomics 18, 226-31.

Matsakas, A., Friedel, A., Hertrampf, T. and Diel, P. (2005) Short-term endurance training results in a muscle-specific decrease of myostatin mRNA content in the rat. Acta Physiologica Scandinavica 183, 299-307.

Matsakas, A., Nikolaidis, M.G., Kokalas, N., Mougios, V. and Diel, P. (2004) Effect of voluntary exercise on the expression of IGF-I and androgen receptor in three rat skeletal muscles and on serum IGF-I and testosterone levels. International Journal of Sports Medicine 25, 502-508.

McTiernan, A., Yasui, Y., Sorensen, B., Irwin, M.L., Morgan, A., Rudolph, R.E., Surawicz, C., Lampe, J.W., Ayub, K., Potter, J.D. and Lampe, P.D. (2006) Effect of a 12-month exercise intervention on patterns of cellular proliferation in colonic crypts: A randomized controlled trial. Cancer Epidemiology, Biomarkers & Prevention 15, 1588-1597.

Murphy, R.M., Watt, K.K., Cameron-Smith, D., Gibbons, C.J. and Snow, R.J. (2003) Effects of creatine supplementation on housekeeping genes in human skeletal muscle using real-time RT-PCR. Physiological Genomics 12, 163-174.

Nehmet, D., Oh, Y., Kim, H.S., Hill, M. and Cooper, D.M. (2002) Effect of intense exercise on inflammatory cytokines and growth mediators in adolescent boys. Pediatrics 110, 681-689.

Ngo, T.H., Barnard, R.J., Tymchuk, C.N., Cohen, P. and Aronson, W.J. (2002) Effect of diet and exercise on serum insulin, IGF-I, and IGFBP-1 levels and growth of LNCaP cells in vitro. Cancer Causes Control 13, 929-935.

Ngyen, U.N., Mougin, F., Simon-Rigaud, M.L., Rouillon, J.D., Marguet, P. and Regnard, J. (1998) Influence of exercise duration on serum insulin-like growth factor and its binding proteins in athletes. European Journal of Applied Physiology and Occupational Physiology 78, 533-537.

Nikolaidis, M.G., Petridou, A., Matsakas, A., Schulz, T., Michna, H. and Mougios, V. (2004) Effect of chronic whel running on the fatty acid composition of phospholipids and triacylglycerols in rat serum, skeletal muscle and heart. Acta Physiologica Scandinavica 181, 199-208.

Pfaffl, M.W., Horgan, G.W. and Dempfle, L. (2002) Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Research 30, 9e36.

Pfaffl, M.W., Tichopad, A., Prgomet, C. and Neuvians, T.P. (2004) Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: BestKeeper--Excel-based tool using pair-wise correlations Biotechnology Letter 26, 509-515.

Quadrilatero, J. and Hoffman-Goetz, L. (2003) Physical activity and colon cancer. A systematic review of potential mechanisms Journal of Sports Medicine and Physical Fitness 43, 121-138.

Raastad, T., Bjoro, T. and Hallen, J. (2000) Hormonal responses to high- and moderate-intensity strength exercise. European Journal of Applied Physiology 82, 121-128.

Rasmussen, R. (2001) Quantification on the LightCycler instrument., Springer-Verlag Press, Heidelberg.

Reddy, B.S., Sugie, S. and Lowenfels, A. (1988) Effect of voluntary exercise on azoxymethane-induced colon carcinogesis in F344 rats. Cancer Research 48, 7079-7081.

Sandhu, M.S., Dunger, D.B. and Giovannucci, E.L. (2002) Insulin, Insulin-like Growth Factor-I (IGF-I), IGF binding proteins, Their biologic interactions, and colorectal cancer. Journal of the National Cancer Institute 94, 972-980.

Schwarz, A.J., Brasel, J.A., Hintz, R.L., Mohan, S. and Cooper, D.M. (1996) Acute effect of brief low- and high-intensity exercise on circulating insulin-like growth factor (IGF) I, II, and IGF-binding protein-3 and its proteolysis in young healthy men. The Journal of Clinical Endocrinology and Metabolism 81, 3492-3497.

Slattery, M.L. (2004) Physical activity and colorectal cancer. Sports Medicine 34, 239-252.

Suikkari, A.M., Sane, T., Seppala, M., Yki-Jarvinen, H., Karonen, S.L. and Koivisto, V.A. (1989) Prolonged exercise increases serum insulin-like growth factor-binding protein concentrations. The Journal of Clinical Endocrinology and Metabolism 68, 141-144.

Thorling, E.B., Jacobsen, N.O. and Overvad, K. (1993) Effect of exercise on intestinal tumor development in the male Fischer rat after exposure to axozymethane. European Journal of Cancer Prevention 2, 77-82.

Thorling, E.B., Jacobsen, N.O. and Overvad, K. (1994) The effect of treadmill exercise on azoxymethane-induced intestinal neoplasia in the male fischer rat on two different high-fat diets. Nutrition and Cancer 22, 31-41.

Tou, J.C.L. and Wade, C.E. (2002) Determinants affecting physical activity levels in animal models. Experimental Biology and Medicine 227, 587-600.

Tymchuk, C.N., Barnard, R.J., Heber, D. and Aronson, W.J. (2001) Evidence of an inhibitory effect of diet and exercise on prostate cancer cell growth. Journal of Urology 166, 1185-1189.

Tymchuk, C.N., Barnard, R.J., Ngo, T.H. and Aronson, W.J. (2002) Role of testosterone, estradiol, and insulin in diet- and exercise-induced reductions in serum-stimulated prostate cancer cell growth in vitro. Nutrition and Cancer 42, 112-116.

Wallace, J.D., Cuneo, R.C., Baxter, R., Orskov, H., Keay, N., Pentecost, C., Dall, R., Rosen, T., Jorgensen, J.O., Cittadini, A., Longobardi, S., Sacca, L., Christiansen, J.S., Bengtsson, B.A. and Sonksen, P.H. (1999) Responses of the growth hormone (GH) and insulin-like growth factor axis to exercise, GH administration, and GH withdrawal in trained adult males: a potential test for GH abuse in sport. The Journal of Clinical Endocrinology and Metabolism 84, 3591-3601.

Yakar, S., Liu, J.L., Fernandez, A.M., Wu, Y., Schally, A. ., Frystyk, J., Chernausek, S.D., Mejia, W. and Le Roith, D. (2001) Liver-specific igf-1 gene deletion leads to muscle insulin insensitivity. Diabetes 50, 1110-1118.

Yakar, S., Liu, J.L., Stannard, B., Butler, A., Accili, D., Sauer, B. and LeRoith, D. (1999) Normal growth and development in the absence of hepatic insulin-like growth factor I. Proceedings of the National Academy of Sciences of the United States of America 96, 7324-7329.

Yeh, J.K., Aloia, J.F., Chen, M., Ling, N., Koo, H.C. and Millard, W.J. (1994) Effect of growth hormone administration and treadmill exercise on serum and skeletal IGF-1 in rats. American Journal of Physiology 266, 129-135.

Zanconato, S., Moromisato, D.Y., Moromisato, M.Y., Woods, J., Brasel, J.A., Leroith, D., Roberts, C.T.J. and Cooper, D.M. (1994) Effect of training and growth hormone suppression on insulin.like growth factor I mRNA in young rats. Journal of Applied Physiology 76, 2204-2209.