JOURNAL OF SPORTS SCIENCE & MEDICINE
http://www.jssm.org
 
Research article
 

LACK OF AGREEMENT BETWEEN GAS EXCHANGE VARIABLES MEASURED BY TWO METABOLIC SYSTEMS

DjordjeG. Jakovljevic1, David Nunan1, Gay Donovan1, Lynette D. Hodges2, Gavin R.H. Sandercock3 and David A. Brodie1

1Research Centre for Society and Health, Buckinghamshire New University, Buckinghamshire, UK
2Department of Sport and Exercise Science, University of Bedfordshire, Bedfordshire, UK
3Centre for Sports and Exercise Science, University of Essex, Colchester, UK

Received   10 September 2007
Accepted   30 October 2007
Published   01 March 2008

© Journal of Sports Science and Medicine (2008) 7, 15 - 22
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ABSTRACT  
The purpose of this study was to assess the agreement and consistency between gas exchange variables measured by two online metabolic systems during an incremental exercise test. After obtaining local ethics approval and informed consent, 15 healthy subjects performed an incremental exercise test to volitional fatigue using the Bruce protocol. The Innocor (Innovision, Denmark) and CardiO2 (Medical Graphics, USA) systems were placed in series, with the Innocor mouthpiece attached to the pneumotach of the CardiO2. Metabolic data were analysed during the last 30 seconds of each stage and at peak exercise. There were non- significant differences (p > 0.05) between the two systems in estimation of oxygen consumption (VO2) and in minute ventilation (VE). Mean Cronbach's alpha for VO2 and VE were 0.88 and 0.92. The Bland-Altman analysis revealed that limits of agreement were -0.52 to 0.55 l.min-1 for VO2, and -8.74 to 10.66 l.min-1 for VE. Carbon dioxide production (VCO2) and consequently respiratory exchange ratio (RER) measured by the Innocor were significantly lower (p < 0.05) through all stages. The CardiO2 measured fraction of expired carbon dioxide (FeCO2) significantly higher (p < 0.05). The limits of agreement for VO2 and VE are wide and unacceptable in cardio-pulmonary exercise testing. The Innocor reported VCO2 systematically lower. Therefore the Innocor and CardiO2 metabolic systems cannot be used interchangeably without affecting the diagnosis of an individual patient. Results from the present study support previous suggestion that considerable care is needed when comparing metabolic data obtained from different automated metabolic systems.

Key words: Metabolic system, oxygen consumption, minute ventilation, carbon dioxide production, Bruce protocol.

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