Figure 1. Mean and standard deviation values of dyspnoea and leg fatigue in 15 smokers (filled bar) and 15 non smoking (empty bar) healthy subjects. Dyspnoea and leg fatigue perception ratings were measured in mm by a 0 - 100 visual analogue scale (VAS) and divided by the maximal workload (watts) for analysis. * p < 0.05 by means of Mann Whitney test.