Figure 2. LDH release from proximal tubules isolated from control and 5-day exhausted rats. LDH release was determined in the basal and ATP-depleted/ Ca+2 overloaded (Antimycin A, 7.5 µM, 2-deoxyglucose, 20 mM and A23187, 10 µM) conditions and expressed a percentage of total LDH. Statistically different from individual basal conditions; * p < 0.001.