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JOURNAL
OF
SPORTS SCIENCE &
MEDICINE
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Research
article
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CIRCUIT RESISTANCE EXERCISE IMPROVES GLYCEMIC CONTROL AND ADIPOKINES IN FEMALES WITH TYPE 2 DIABETES MELLITUS |
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Sunghwun Kang1,2, Jin Hee Woo1, Ki Ok Shin1, Dukkuy Kim3, Hye-Jeong Lee2, Young Jun Kim1 and Nam Hwoeh Yeo1  |
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1Laboratory of Exercise Physiology, Department of Physical Education, 2Department of Pharmacology, and 3Department of Internal Medicine, Medical Sciences Research Institute, College of Medicine, Dong-A University, Republic of Korea. |
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© Journal of Sports Science and Medicine (2009) 8, 682 - 688 |
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| ABSTRACT | |||
| The aim of study was to evaluate whether circuit resistance exercise
(CE) improves glycemic control and adipokine levels in comparison with walking
exercise (WE) in 15 adult postmenopausal Korean females with type 2 diabetes
mellitus (T2DM). The participants were randomly assigned to either the CE
or WE group. Subjects exercised for 1 h, three times per week for 12 weeks.
The parameters measured were body composition, respiratory rate, blood glucose,
insulin and adipokines. The body composition of the CE group showed a significant
reduction (all p < 0.05) in body weight, body mass index (BMI), and percentage
of body fat and a significant increase in muscle mass. Respiratory function
was also significantly increased in the CE group. Additionally, hemoglobin
A1c (HbA1c) changed favorably in the CE group, as were the concentrations
of adipokines such as retinol binding protein 4 (RBP-4) (p < 0.05), adiponectin
(p < 0.01), and monocyte chemoattractant protein-1 (MCP-1) (p < 0.01).
In addition, significant correlations with CE were evident for homeostatic
model assessment insulin resistance (HOMA-IR) and glucose (r = 0.69, p <
0.001), muscle mass and glucose (r = 0.45, p < 0.05), and muscle mass
and HbA1c (r = 0.39, p < 0.05). The beneficial effects of CE include
the development of muscle mass, which effectively increases glucose use
and reduces the amount of insulin required. Thus, our results suggest that
CE improves glycemic control and adipokines resulting from incrementally
increased muscle mass and reductions of body weight, BMI and percentage
of body fat for T2DM postmenopausal Korean women.
Key words: Circuit resistance exercise, walking exercise, glycemic control, adipokines, type 2 diabetes. |
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