Supplementary Materials

 
Table S2. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia.
Characteristic Event, n Model 1 Model 2 Model 3
HR 95% CI p HR 95% CI p HR 95% CI p
CTI (per 1-unit increase) 1776 1.10 1.01-1.19 <0.05 1.11 1.02-1.21 <0.05 1.11 1.01-1.21 <0.05
Q1 (Ref) 339 Ref Ref Ref
Q2 398 1.06 0.92-1.23 0.43 1.00 0.87-1.16 0.97 1.03 0.92-1.17 0.63
Q3 483 1.06 0.92-1.22 0.44 1.12 0.97-1.30 0.13 1.07 0.94-1.22 0.27
Q4 556 1.25 1.09-1.44 <0.05 1.15 0.99-1.33 0.07 1.12 1.01-1.27 <0.05
P for trend <0.05 <0.05 <0.05
HR = hazard ratio; CI = confidence interval. Model 1: unadjusted; Model 2: adjusted for sex, age, residence, marital status, education, smoking, and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates.

 

 
Table S3. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia according to sex.
Sex Characteristic Event, n Model 1 Model 2 Model 3
HR 95% CI p HR 95% CI p HR 95% CI p
Male CTI (per 1-unit) 680 1.21 1.05-1.39 <0.05 1.23 1.07-1.41 <0.05 1.21 1.05-1.42 <0.05
Q1 (Ref) 138 Ref Ref Ref
Q2 153 1.10 0.86-1.41 0.45 1.04 0.81-1.33 0.77 1.05 0.83-1.32 0.61
Q3 182 1.17 0.92-1.49 0.20 1.25 0.98-1.60 0.07 1.17 0.94-1.45 0.10
Q4 207 1.43 1.13-1.81 <0.05 1.29 1.01-1.65 <0.05 1.25 1.03-1.55 <0.05
P for trend <0.05 <0.05 <0.05
Female CTI (per 1-unit) 1,096 1.15 1.05-1.26 <0.05 1.16 1.06-1.28 <0.05 1.16 1.05-1.28 <0.05
Q1 (Ref) 201 Ref Ref Ref
Q2 245 1.15 0.95-1.40 0.12 1.16 0.96-1.41 0.10 1.16 0.96-1.44 0.07
Q3 301 1.22 1.02-1.46 <0.05 1.23 1.03-1.48 <0.05 1.22 1.03-1.51 <0.05
Q4 349 1.41 1.18-1.69 <0.05 1.40 1.17-1.68 <0.05 1.42 1.16-1.67 <0.05
P for trend <0.05 <0.05 <0.05
HR = hazard ratio; CI = confidence interval. Model 1: unadjusted; Model 2: adjusted for age, residence, marital status, education, smoking, and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates.

 

 
Table S4. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia according to age group.
Age group Characteristic Event, n Model 1 Model 2 Model 3
HR 95% CI p HR 95% CI p HR 95% CI p
45-59 years CTI (per 1-unit) 1042 1.20 1.08-1.34 <0.05 1.19 1.07-1.33 <0.05 1.16 1.04-1.31 <0.05
Q1 (Ref) 198 Ref Ref Ref
Q2 236 1.12 0.89-1.40 0.33 1.11 0.88-1.39 0.36 1.11 0.88-1.37 0.35
Q3 289 1.34 1.07-1.67 <0.05 1.33 1.06-1.67 <0.05 1.33 1.04-1.65 <0.05
Q4 319 1.58 1.27-1.97 <0.05 1.56 1.25-1.95 <0.05 1.52 1.21-1.94 <0.05
P for trend <0.05 <0.05 <0.05
≥60 years CTI (per 1-unit) 734 1.14 1.02-1.28 <0.05 1.13 1.01-1.27 <0.05 1.11 1.01-1.25 <0.05
Q1 (Ref) 141 Ref Ref Ref
Q2 166 1.09 0.84-1.42 0.52 1.08 0.83-1.41 0.56 1.05 0.81-1.38 0.61
Q3 192 1.26 0.97-1.63 0.09 1.24 0.96-1.61 0.10 1.21 0.94-1.62 0.11
Q4 235 1.41 1.10-1.81 <0.05 1.39 1.08-1.79 <0.05 1.36 1.05-1.76 <0.05
P for trend <0.05 <0.05 <0.05
HR = hazard ratio; CI = confidence interval. Model 1: unadjusted; Model 2: adjusted for sex, residence, marital status, education, smoking, and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates.

 

 
Table S5. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia according to physical activity.
Physical activity Characteristic Event, n Model 1 Model 2 Model 3
HR 95% CI p HR 95% CI p HR 95% CI p
Light CTI (per 1-unit) 559 1.60 1.20-2.13 <0.05 1.61 1.19-2.16 <0.05 1.61 1.20-2.17 <0.05
Q1 (Ref) 108 Ref Ref Ref
Q2 124 0.77 0.47-1.27 0.31 0.79 0.48-1.31 0.36 0.81 0.48-1.36 0.41
Q3 150 0.98 0.60-1.58 0.93 0.95 0.58-1.56 0.85 0.95 0.56-1.57 0.85
Q4 177 1.87 1.19-2.95 <0.05 1.86 1.17-2.96 <0.05 1.91 1.21-3.05 <0.05
P for trend <0.05 <0.05 <0.05
Moderate CTI (per 1-unit) 863 1.56 1.41-1.73 <0.05 1.56 1.41-1.73 <0.05 1.54 1.42-1.74 <0.05
Q1 (Ref) 143 Ref Ref Ref
Q2 191 1.18 0.98-1.42 0.08 1.18 0.98-1.42 0.07 1.17 0.97-1.43 0.07
Q3 254 1.78 1.49-2.12 <0.05 1.80 1.51-2.15 <0.05 1.82 1.53-2.17 <0.05
Q4 275 2.02 1.70-2.40 <0.05 2.01 1.69-2.40 <0.05 2.02 1.66-2.41 <0.05
P for trend <0.05 <0.05 <0.05
Vigorous CTI (per 1-unit) 354 1.40 1.11-1.76 <0.05 1.43 1.13-1.81 <0.05 1.43 1.13-1.84 <0.05
Q1 (Ref) 76 Ref Ref Ref
Q2 83 1.24 0.84-1.81 0.28 1.21 0.82-1.79 0.33 1.21 0.82-1.78 0.36
Q3 81 1.17 0.80-1.72 0.42 1.13 0.77-1.67 0.54 1.12 0.73-1.65 0.60
Q4 114 1.66 1.15-2.40 <0.05 1.66 1.14-2.42 <0.05 1.67 1.14-2.47 <0.05
P for trend <0.05 <0.05 <0.05
HR = hazard ratio; CI = confidence interval. Model 1: unadjusted; Model 2: adjusted for sex, age, residence, marital status, education, and smoking and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates.

 

 
Table S6. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia.
Characteristic Event, n Model 1 Model 2 Model 3
HR 95% CI p HR 95% CI p HR 95% CI p
CTI (per 1-unit) 1691 1.14 1.07-1.22 <0.05 1.13 1.06-1.21 <0.05 1.11 1.04-1.22 <0.05
Q1 (Ref) 282 Ref Ref Ref
Q2 405 1.08 0.90-1.28 0.40 1.07 0.89-1.28 0.44 1.04 0.86-1.27 0.41
Q3 496 1.42 1.19-1.70 <0.05 1.40 1.17-1.68 <0.05 1.36 1.14-1.67 <0.05
Q4 508 1.78 1.48-2.14 <0.05 1.75 1.45-2.11 <0.05 1.71 1.40-2.05 <0.05
P for trend <0.05 <0.05 <0.05
HR = hazard ratio; CI = confidence interval. Model 1: unadjusted; Model 2: adjusted for sex, age, residence, marital status, education, smoking, and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates.

 

 
Table S7. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia according to sex.
Sex Characteristic Event, n Model 1 Model 2 Model 3
HR 95% CI p HR 95% CI p HR 95% CI p
Male CTI (per 1-unit) 689 1.16 1.05-1.28 <0.05 1.15 1.04-1.27 <0.05 1.11 1.01-1.27 <0.05
Q1 (Ref) 120 Ref Ref Ref
Q2 173 1.09 0.82-1.44 0.55 1.07 0.81-1.42 0.61 1.05 0.81-1.43 0.61
Q3 197 1.43 1.09-1.87 <0.05 1.41 1.07-1.85 <0.05 1.37 1.04-1.81 <0.05
Q4 199 1.72 1.32-2.23 <0.05 1.69 1.30-2.20 <0.05 1.66 1.26-2.16 <0.05
P for trend <0.05 <0.05 <0.05
Female CTI (per 1-unit) 1002 1.12 1.03-1.21 <0.05 1.11 1.02-1.20 <0.05 1.11 1.02-1.17 <0.05
Q1 (Ref) 162 Ref Ref Ref
Q2 232 1.07 0.85-1.34 0.56 1.06 0.84-1.34 0.60 1.04 0.82-1.34 0.65
Q3 299 1.38 1.11-1.71 <0.05 1.37 1.10-1.70 <0.05 1.35 1.08-1.68 <0.05
Q4 309 1.65 1.33-2.06 <0.05 1.62 1.30-2.04 <0.05 1.62 1.27-2.04 <0.05
P for trend <0.05 <0.05 <0.05
HR = hazard ratio; CI = confidence interval. Model 1: unadjusted; Model 2: adjusted for age, residence, marital status, education, smoking, and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates.

 

 
Table S8. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia according to age group.
Age group Characteristic Event, n Model 1 Model 2 Model 3
HR 95% CI p HR 95% CI p HR 95% CI p
45-59 CTI (per 1-unit) 1010 1.19 1.09-1.29 <0.05 1.18 1.08-1.29 <0.05 1.15 1.06-1.28 <0.05
Q1 (Ref) 185 Ref Ref Ref
Q2 237 1.09 0.86-1.39 0.48 1.08 0.85-1.38 0.52 1.05 0.81-1.36 0.51
Q3 295 1.46 1.17-1.83 <0.05 1.44 1.15-1.81 <0.05 1.41 1.12-1.78 <0.05
Q4 293 1.82 1.45-2.29 <0.05 1.79 1.43-2.26 <0.05 1.78 1.40-2.21 <0.05
P for trend <0.05 <0.05 <0.05
≥60 CTI (per 1-unit) 681 1.09 0.98-1.22 0.11 1.08 0.97-1.21 0.13 1.05 0.94-1.21 0.13
Q1 (Ref) 97 Ref Ref Ref
Q2 141 1.10 0.81-1.48 0.55 1.08 0.80-1.46 0.59 1.05 0.78-1.44 0.55
Q3 200 1.33 1.02-1.73 <0.05 1.31 1.00-1.71 <0.05 1.31 0.97-1.71 0.06
Q4 243 1.57 1.22-2.03 <0.05 1.55 1.20-2.00 <0.05 1.52 1.17-1.98 <0.05
P for trend <0.05 <0.05 <0.05
HR = hazard ratio; CI = confidence interval. Model 1: unadjusted; Model 2: adjusted for sex, residence, marital status, education, smoking, and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates.

 

 
Table S9. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia according to physical activity.
Physical activity Characteristic Event, n Model 1 Model 2 Model 3
HR 95% CI p HR 95% CI p HR 95% CI p
Light CTI (per 1-unit) 634 1.13 1.01-1.27 <0.05 1.12 1.00-1.26 <0.05 1.12 0.97-1.26 0.06
Q1 (Ref) 122 Ref Ref Ref
Q2 141 1.02 0.78-1.34 0.88 1.01 0.77-1.33 0.91 1.01 0.75-1.31 0.91
Q3 170 1.15 0.89-1.49 0.28 1.14 0.88-1.48 0.31 1.12 0.88-1.45 0.32
Q4 201 1.39 1.08-1.78 <0.05 1.38 1.07-1.77 <0.05 1.34 1.05-1.74 <0.05
P for trend <0.05 <0.05 <0.05
Moderate CTI (per 1-unit) 982 1.15 1.06-1.26 <0.05 1.14 1.05-1.25 <0.05 1.12 1.03-1.25 <0.05
Q1 (Ref) 163 Ref Ref Ref
Q2 218 1.09 0.83-1.43 0.53 1.08 0.82-1.42 0.57 1.05 0.82-1.43 0.59
Q3 290 1.47 1.15-1.88 <0.05 1.45 1.13-1.86 <0.05 1.41 1.11-1.84 <0.05
Q4 311 1.68 1.32-2.13 <0.05 1.66 1.31-2.11 <0.05 1.62 1.27-2.08 <0.05
P for trend <0.05 <0.05 <0.05
Vigorous CTI (per 1-unit) 395 1.21 1.02-1.44 <0.05 1.20 1.01-1.43 <0.05 1.17 1.01-1.41 0.05
Q1 (Ref) 95 Ref Ref Ref
Q2 89 1.08 0.75-1.57 0.68 1.07 0.74-1.56 0.71 1.05 0.72-1.53 0.72
Q3 82 1.28 0.89-1.85 0.18 1.27 0.88-1.83 0.20 1.24 0.85-1.83 0.20
Q4 129 1.61 1.16-2.23 <0.05 1.59 1.15-2.21 <0.05 1.56 1.12-2.17 <0.05
P for trend <0.05 <0.05 <0.05
HR = hazard ratio; CI = confidence interval. Model 1: unadjusted; Model 2: adjusted for sex, age, residence, marital status, education, and smoking and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates.

 

 
Table S10. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia.
Characteristic Event, n Model 1 Model 2 Model 3
HR 95% CI p HR 95% CI p HR 95% CI p
CTI (per 1-unit increase) 1980 1.54 1.40-1.69 <0.05 1.53 1.39-1.68 <0.05 1.51 1.36-1.68 <0.05
Q1 (Ref) 377 Ref Ref Ref
Q2 445 1.05 0.90-1.22 0.52 1.04 0.89-1.21 0.57 1.02 0.85-1.21 0.58
Q3 540 1.56 1.34-1.82 <0.05 1.54 1.32-1.80 <0.05 1.51 1.31-1.76 <0.05
Q4 618 1.97 1.70-2.28 <0.05 1.94 1.67-2.25 <0.05 1.92 1.62-2.21 <0.05
P for trend <0.05 <0.05 <0.05
HR = hazard ratio; CI = confidence interval. Model 1: unadjusted; Model 2: adjusted for sex, age, residence, marital status, education level, smoking, and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates.

 

 
Table S11. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia according to sex.
Sex Characteristic Event, n Model 1 Model 2 Model 3
HR 95% CI p HR 95% CI p HR 95% CI p
Male CTI (per 1-unit) 771 1.48 1.29-1.69 <0.05 1.47 1.28-1.69 <0.05 1.44 1.25-1.65 <0.05
Q1 (Ref) 144 Ref Ref Ref
Q2 170 1.06 0.85-1.32 0.58 1.05 0.84-1.31 0.61 1.04 0.81-1.31 0.60
Q3 212 1.61 1.27-2.05 <0.05 1.59 1.25-2.02 <0.05 1.56 1.22-2.03 <0.05
Q4 245 1.93 1.54-2.43 <0.05 1.90 1.51-2.40 <0.05 1.85 1.47-2.34 <0.05
P for trend <0.05 <0.05 <0.05
Female CTI (per 1-unit) 1209 1.59 1.41-1.79 <0.05 1.61 1.43-1.82 <0.05 1.61 1.42-1.85 <0.05
Q1 (Ref) 233 Ref Ref Ref
Q2 275 1.07 0.87-1.31 0.52 1.08 0.88-1.32 0.49 1.07 0.87-1.31 0.42
Q3 328 1.58 1.29-1.92 <0.05 1.60 1.30-1.95 <0.05 1.62 1.32-1.93 <0.05
Q4 373 2.01 1.66-2.43 <0.05 2.04 1.68-2.47 <0.05 2.04 1.71-2.53 <0.05
P for trend <0.05 <0.05 <0.05
HR = hazard ratio; CI = confidence interval. Model 1: unadjusted; Model 2: adjusted for age, residence, marital status, education level, smoking, and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates.

 

 
Table S12. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia according to age group.
Age group Characteristic Event, n Model 1 Model 2 Model 3
HR 95% CI p HR 95% CI p HR 95% CI p
45-59 CTI (per 1-unit) 1165 1.65 1.47-1.85 <0.05 1.66 1.48-1.87 <0.05 1.65 1.46-1.85 <0.05
Q1 (Ref) 215 Ref Ref Ref
Q2 246 1.10 0.89-1.36 0.36 1.10 0.89-1.35 0.37 1.07 0.85-1.34 0.37
Q3 319 1.65 1.35-2.01 <0.05 1.64 1.34-2.00 <0.05 1.63 1.33-2.01 <0.05
Q4 385 2.20 1.80-2.67 <0.05 2.22 1.81-2.71 <0.05 2.23 1.82-2.73 <0.05
P for trend <0.05 <0.05 <0.05
≥60 CTI (per 1-unit) 815 1.38 1.20-1.58 <0.05 1.35 1.17-1.55 <0.05 1.35 1.15-1.57 <0.05
Q1 (Ref) 162 Ref Ref Ref
Q2 181 1.07 0.84-1.37 0.57 1.06 0.83-1.36 0.59 1.05 0.82-1.38 0.54
Q3 221 1.39 1.09-1.77 <0.05 1.35 1.06-1.72 <0.05 1.36 1.05-1.73 <0.05
Q4 251 1.59 1.25-2.02 <0.05 1.51 1.18-1.94 <0.05 1.51 1.17-1.94 <0.05
P for trend <0.05 <0.05 <0.05
HR = hazard ratio; CI = confidence interval. Model 1: unadjusted; Model 2: adjusted for sex, residence, marital status, education level, smoking, and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates.

 

 
Table S13. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia according to physical activity.
Physical activity Characteristic Event, n Model 1 Model 2 Model 3
HR 95% CI p HR 95% CI p HR 95% CI p
Light activity CTI (per 1-unit) 191 1.59 1.20-2.11 <0.05 1.61 1.21-2.15 <0.05 1.61 1.21-2.16 <0.05
Q1 (Ref) 44 Ref Ref Ref
Q2 36 1.01 0.65-1.58 0.94 1.02 0.65-1.59 0.92 1.01 0.64-1.62 0.85
Q3 43 1.05 0.68-1.62 0.83 1.04 0.67-1.61 0.85 1.04 0.66-1.63 0.82
Q4 68 1.85 1.18-2.90 <0.05 1.86 1.18-2.93 <0.05 1.91 1.21-2.97 <0.05
P for trend <0.05 <0.05 <0.05
Moderate activity CTI (per 1-unit) 982 1.54 1.38-1.71 <0.05 1.55 1.39-1.73 <0.05 1.53 1.37-1.74 <0.05
Q1 (Ref) 268 Ref Ref Ref
Q2 305 1.04 0.86-1.25 0.70 1.04 0.86-1.25 0.71 1.04 0.85-1.25 0.64
Q3 415 1.76 1.47-2.11 <0.05 1.78 1.48-2.14 <0.05 1.77 1.47-2.13 <0.05
Q4 453 1.99 1.67-2.38 <0.05 1.98 1.66-2.37 <0.05 1.98 1.65-2.37 <0.05
P for trend <0.05 <0.05 <0.05
Vigorous activity CTI (per 1-unit) 607 1.39 1.11-1.76 <0.05 1.41 1.13-1.79 <0.05 1.41 1.12-1.83 <0.05
Q1 (Ref) 65 Ref Ref Ref
Q2 91 1.09 0.81-1.46 0.59 1.08 0.80-1.45 0.61 1.07 0.81-1.46 0.53
Q3 86 1.16 0.79-1.71 0.43 1.14 0.77-1.68 0.50 1.14 0.74-1.68 0.51
Q4 135 1.63 1.14-2.34 <0.05 1.62 1.13-2.33 <0.05 1.65 1.15-2.37 <0.05
P for trend <0.05 <0.05 <0.05
HR = hazard ratio; CI = confidence interval. Model 1: unadjusted; Model 2: adjusted for sex, residence, marital status, education level, and smoking and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates .

 

 
Table S14. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia based on logistic regression models.
Characteristic Event, n Model 1 Model 2 Model 3
OR 95% CI p OR 95% CI p OR 95% CI p
CTI (per 1 unit) 2011 1.13 1.04-1.23 0.02 1.13 1.04-1.23 0.02 1.12 1.01-1.21 0.03
Q1 (Ref) 474 1.00 1.00 1.00
Q2 484 1.05 0.91-1.21 0.80 1.04 0.90-1.20 0.89 1.03 0.91-1.22 0.82
Q3 508 1.11 0.97-1.27 0.34 1.08 0.94-1.24 0.54 1.07 0.93-1.23 0.44
Q4 545 1.19 1.04-1.36 0.03 1.18 1.03-1.35 0.04 1.17 1.01-1.33 0.04
P for trend 1.06 1.02-1.11 0.02 1.06 1.02-1.11 0.02 1.04 1.01-1.14 0.02
OR = odds ratio; CI = confidence interval. Q1 represents the lowest quartile and was used as the reference group. Model 1: unadjusted; Model 2: adjusted for sex, age, residence, marital status, education, smoking, and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates. P for trend was calculated by entering the median value of each quartile as a continuous variable in the logistic regression model.

 

 
Table S15. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia according to sex based on logistic regression models.
Sex Characteristic Event, n Model 1 Model 2 Model 3
OR 95% CI p OR 95% CI p OR 95% CI p
Male CTI (per 1-unit) 785 1.25 1.09-1.43 0.01 1.23 1.08-1.41 0.01 1.22 1.06-1.41 0.01
Q1 (Ref) 148
Q2 178 1.11 0.89-1.39 0.53 1.09 0.88-1.36 0.65 1.12 0.87-1.37 0.50
Q3 214 1.02 0.83-1.26 0.85 0.98 0.79-1.20 0.62 0.97 0.81-1.23 0.71
Q4 245 1.32 1.07-1.63 0.02 1.28 1.04-1.58 0.04 1.31 1.05-1.62 0.03
P for trend 0.04 0.07 0.05
Female CTI (per 1-unit) 1226 1.07 0.97-1.17 0.41 1.07 0.97-1.17 0.40 1.05 0.97-1.15 0.56
Q1 (Ref) 232
Q2 270 1.02 0.86-1.22 0.86 1.02 0.86-1.22 0.81 1.02 0.85-1.22 0.75
Q3 328 1.17 0.98-1.39 0.16 1.15 0.96-1.37 0.24 1.12 0.94-1.37 0.30
Q4 396 1.13 0.96-1.33 0.31 1.13 0.96-1.33 0.33 1.12 0.93-1.32 0.42
P for trend 0.15 0.16 0.22
OR = odds ratio; CI = confidence interval. Q1 represents the lowest quartile and was used as the reference group. Model 1: unadjusted; Model 2: adjusted for age, residence, marital status, education level, smoking, and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates. P for trend was calculated by entering the median value of each quartile as a continuous variable in the logistic regression model.

 

 
Table S16. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia according to age group based on logistic regression models.
Age group Characteristic Event, n Model 1 Model 2 Model 3
OR 95% CI p OR 95% CI p OR 95% CI p
45-59 CTI (per 1-unit) 1229 1.29 1.13-1.47 0.01 1.27 1.12-1.45 0.01 1.24 1.12-1.41 0.01
Q1 (Ref) 220
Q2 280 1.09 0.88-1.35 0.65 1.08 0.87-1.33 0.70 1.05 0.86-1.33 0.70
Q3 320 1.16 0.93-1.44 0.32 1.14 0.91-1.41 0.38 1.14 0.92-1.41 0.42
Q4 409 1.45 1.16-1.82 0.01 1.43 1.15-1.79 0.01 1.42 1.13-1.75 0.01
P for trend 0.01 0.01 0.01
≥60 CTI (per 1-unit) 782 1.19 1.05-1.35 0.02 1.18 1.04-1.33 0.03 1.15 1.02-1.31 0.04
Q1 (Ref) 180
Q2 190 1.12 0.89-1.41 0.52 1.11 0.88-1.39 0.56 1.11 0.85-1.36 0.56
Q3 200 1.19 0.95-1.50 0.23 1.18 0.94-1.48 0.25 1.15 0.91-1.45 0.25
Q4 212 1.36 1.08-1.72 0.02 1.34 1.06-1.67 0.03 1.31 1.04-1.64 0.04
P for trend 0.02 0.03 0.04
OR = odds ratio; CI = confidence interval. Q1 represents the lowest quartile and was used as the reference group. Model 1: unadjusted; Model 2: adjusted for sex, residence, marital status, education level, smoking, and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates. P for trend was calculated by entering the median value of each quartile as a continuous variable in the logistic regression model.

 

 
Table S17. Association between the C-reactive protein - triglyceride - glucose index (CTI) and incident dyslipidemia according to physical activity level based on logistic regression models.
Physical activity Characteristic Event, n Model 1 Model 2 Model 3
OR 95% CI p OR 95% CI p OR 95% CI p
Light CTI (per 1-unit) 634 1.15 1.05-1.25 0.03 1.14 1.04-1.23 0.04 1.12 1.04-1.19 0.04
Q1 (Ref) 122
Q2 141 1.07 0.90-1.27 0.72 1.06 0.90-1.26 0.76 1.07 0.89-1.24 0.76
Q3 170 1.11 0.94-1.32 0.33 1.10 0.93-1.31 0.36 1.05 0.97-1.32 0.35
Q4 201 1.29 1.08-1.54 0.02 1.27 1.07-1.51 0.03 1.23 1.09-1.54 0.03
P for trend 0.02 0.03 0.03
Moderate CTI (per 1-unit) 982 1.16 1.06-1.26 0.01 1.15 1.05-1.25 0.02 1.11 1.01-1.24 0.02
Q1 (Ref) 163
Q2 218 1.05 0.89-1.24 0.90 1.05 0.89-1.24 0.91 1.02 0.84-1.20 0.91
Q3 290 1.13 0.96-1.33 0.25 1.12 0.95-1.32 0.28 1.10 0.92-1.28 0.32
Q4 311 1.33 1.13-1.56 0.01 1.31 1.12-1.54 0.01 1.32 1.12-1.53 0.02
P for trend 0.01 0.02 0.02
Vigorous CTI (per 1-unit) 395 1.34 1.11-1.61 0.01 1.33 1.11-1.60 0.01 1.30 1.13-1.60 0.02
Q1 (Ref) 95
Q2 89 1.22 0.87-1.71 0.33 1.20 0.86-1.67 0.35 1.17 0.81-1.62 0.37
Q3 82 1.30 0.93-1.81 0.15 1.28 0.92-1.78 0.18 1.25 0.92-1.75 0.22
Q4 129 1.54 1.15-2.08 0.01 1.52 1.13-2.04 0.02 1.51 1.12-1.96 0.02
P for trend 0.01 0.02 0.02
OR = odds ratio; CI = confidence interval. Q1 represents the lowest quartile and was used as the reference group. Model 1: unadjusted; Model 2: adjusted for sex, residence, marital status, education level, and smoking and drinking; Model 3: Further adjusted for chronic diseases (joint disease, liver disease, asthma, kidney disease, and gastrointestinal disease), as well as the use of anti-diabetic medication, anti-hypertensive medication, and lipid-lowering medication as covariates. P for trend was calculated by entering the median value of each quartile as a continuous variable in the logistic regression model.