Table 4. Biomarkers of oxidative (pre) and after (post) 3 weeks exercise training in normoxia (NT) and hypoxia (HT).
Variables NT, n=12 HT, n=12 Main effects (p-value, ηp2)
Pre Post Pre Post Ox T Ex Ox*T Ox*Ex T*Ex Ox*T*Ex
SOD
[U/gHb]
rest 1248.2 ± 92.4 1215.1 ± 78.0 1250.0 ± 108.0 1152.5 ± 115.5 0.233
(0.126)
0.708
(0.031)
0.001
(0.615)
0.961
(0.000)
0.008
(0.484)
0.193
(0.148)
0.498
(0.043)
max 1195.2 ± 59.5 1195.0 ± 59.3 1195.0 ± 68.9 1250.6 ± 54.1
GPX
[U/gHb]
rest 47.0 ± 6.5 48.0 ± 8.5 48.1 ± 8.2 54.2 ± 6.1 0.008
(0.482)
0.034
(0.347)
0.000
(0.733)
0.104
(0.222)
0.175
(0.160)
0.501
(0.042)
0.147
(0.181)
max 54.7 ± 7.4 55.0 ± 9.4 55.7 ± 6.9 58.3 ± 8.6
CAT
[U/gHb]
rest 214.9 ± 38.5 219.6 ± 33.0 224.3 ± 27.9 234.5 ± 38.6 0.228
(0.129)
0.085
(0.246)
0.000
(0.785)
0.298
(0.098)
0.692
(0.015)
0.351
(0.079)
0.804
(0.006)
max 229.6 ± 18.6 232.5 ± 17.2 230.6 ± 15.4 235.8 ± 6.5
GSH
[μg/mgHb]
rest 2.9 ± 0.5 2.9 ± 0.7 2.9 ± 0.5 2.8 ± 0.5 0.365
(0.075)
0.221
(0.133)
0.020
(0.404)
0.025
(0.379)
0.010
(0.468)
0.366
(0.075)
0.092
(0.237)
max 3.0 ± 0.5 3.1 ± 0.5 3.2 ± 0.7 2.7 ± 0.4#
SOD-superoxide dismutase; GPX- glutathione peroxidase; CAT-catalase; GSH- reduced glutathione. Ox-oxygen conditions; T-training and Ex-exercise effects. Data are means and SD.#p < 0.05 significant differences between post - HT vs. post – NT.