| 1 |
Question
/objective is sufficiently described? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
| 2 |
Study design
is evident and appropriate? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
| 3 |
Method of
subject/comparison group selection or source of information/input variables
is described and appropriate? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
| 4 |
Subject (and
comparison group, if applicable) characteristics are sufficiently described? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
| 5 |
If interventional
and random allocation was possible, was it described? |
0 |
0 |
2 |
0 |
0 |
1 |
0 |
1 |
2 |
1 |
0 |
2 |
2 |
| 6 |
If interventional
and blinding of investigators was possible, was it reported? |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
1 |
0 |
1 |
1 |
0 |
1 |
| 7 |
If interventional
and blinding of subjects was possible, was it reported? |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
| 8 |
Outcome(s)
and (if applicable) exposure measure(s) is/are well defined and robust to
measurement/misclassification bias? Means of assessment are reported? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
| 9 |
Sample size
is appropriate? |
1 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
1 |
2 |
| 10 |
Analytic
methods are described/justified and appropriate? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
| 11 |
Some estimate
of variance is reported for the main results? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
| 12 |
Controlled
for confounding? |
1 |
1 |
2 |
1 |
1 |
1 |
2 |
1 |
1 |
1 |
1 |
2 |
1 |
| 13 |
Results reported
in sufficient detail? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
| 14 |
Conclusions
supported by the results? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
| Summary
score (total sum / total possible sum) |
0.77 |
0.81 |
0.92 |
0.81 |
0.81 |
0.88 |
0.85 |
0.88 |
0.81 |
0.88 |
0.88 |
0.88 |
0.92 |
