Table 1. Synthesis of the studied pertinent to nerve responses to stretching. Author Year Stretching Protocol N Location Duration Measures Assessment Pre Post Andrade et al 2018 Passive Ankle dorsiflexion 15 Sciatic Nerve 1 session ROM, SWV PS – 6 minutes Resting conditions ROM = 6.4 ± 2.6° SWV =-13.3±7.9% Andrade et al 2020 Nerve directed stretching Ankle dorsiflexion 21 Sciatic and Tibia Nerves 60 sessions ROM, SWVs, SWSt PS – 3 hours ROM = 35.7 ± 6.6° SWVs = 6.1 ± 1.5 m/s SWVt = 7.3 ± 1.4 m/s ROM =36.3 ± 6.1° SWVs = 4.9 ± 1.3 m/s SWVt = 6.3 ± 1.3 m/s Beltran-Alacreu et al 2015 Neural gliding Supine body flexion 45 Posterior Nerve Cords 1 session PPT (left side) PS – 5 minutes M = 1.94 ± 0.14kg; T = 2.14 ± 0.54kg; SUB = 2.56 ± 0.88kg TRAP = 3.88 ± 0.88kg TIB = 5.18 ± 1.80kg M = 2.52 ± 0.16kg; T = 2.31 ± 0.62kg; SUB = 3.01 ± 1.13kg TRAP = 4.17 ± 1.54kg TIB = 5.64 ± 1.89kg Coppieters et al 2009 Neural gliding Elbow extension + cervical ipsilateral flexion 15 Median Nerve 1 session LNG DS Resting conditions LNG = 10.2 ± 2.8 mm Coppieters et al 2009 Neural tensioning Elbow extension + cervical contralateral flexion 15 Median Nerve 1 session LNG DS Resting conditions LNG= 3.6 ± 2.3 mm Echigo et al 2008 Neural gliding Elbow extension with forearm supination 34 Median Nerve 1 session LNG DS Resting conditions LNG = 3.0 ± 1.81 mm Echigo et al 2008 Neural gliding Elbow flexion with forearm supination 34 Median Nerve 1 session LNG DS Resting conditions LNG = 3.0 ± 1.34 mm Ellis et al 2008 Neural mobilization Knee extension 27 Sciatic Nerve 1 session LNM, PNM, LNG Popliteal fossa DS Resting conditions LNM = 6.62mm PNM = 3.26mm LNG = 5.22mm Gamelas et al 2019 Neural tensioning 4 sets - 10 reps with a 1 minute rest. Each repetition was performed at a rhythm of 6s. 15 Median Nerve 1 session PPT, VAS Th=Thenar Fr= Forearm PS – immediately PPT Fr = 34.75 ± 14.41kg VAS Fr = 3.30 ± 1.76 PPT Th = 42.35 ± 15.8kg VAS Th = 3.83 ± 2.15 PPT Fr = 40.0 ± 13.77kg VAS Fr = 3.23 ± 2.01 PPT Th = 46.22 ± 15.72kg VAS Th = 3.27 ± 2.36 Gamelas et al 2019 Neural gliding 4 sets - 10 reps with a 1 minute rest. Each repetition was performed at a rhythm of 6s. 15 Median Nerve 1 session PPT, VAS Th=Thenar Fr= Forearm PS – immediately PPT Fr = 39.11 ± 14.54kg VAS Fr = 3.60 ± 2.51 PPT Th = 46.38 ± 14.54 kg VAS Th = 3.67 ± 2.66 PPT Fr = 40.97 ± 14.25 kg VAS Fr = 3.43 ± 2.37 PPT Th = 47.89 ± 13.50 kg VAS Th = 3.57 ± 2.66 Jaberzadeh et al 2005 Elbow extension Passive elbow extension 26 Median Nerve 1 session RT DS RT =0.8 Nm Pain onset=3° RT = 3.9 Nm Pain onset = 45° Lee et al 2017 Passive stretching (s) 5 sets - 40 sec with a 20 second rest 22 Hamstrings 9 sessions PPT, VAS, ROM, ODI PS - 30 minutes PPTs = 14.6 ± 2.9; VASs = 5.4 ± 0.8; ROMs = 46.3 ± 8.9 ODIs = 29.7 ± 8.9 PPTs = 17.3 ± 3.1; VASs = 2.1 ± 0.7 ROMs = 51.6 ± 9.7 ODIs = 17.8 ± 5.1 Lee et al 2017 Neural mobilization (nm) 5 sets 20 reps - 40 sec with a 20 second rest 22 Hamstrings 9 sessions PPT, VAS, ROM, ODI PS - 30 minutes PPTnm = 14.5 ± 4.6; VASnm = 5.6 ± 1.0; ODInm =26.4 ± 4.9 ROMnm = 49.4 ± 10.7 PPTnm =18.4 ± 3.9; VASnm = 1.4 ± 0.8; ODInm =14.2 ± 3.8 ROMnm = 55.8 ± 10.2 Martínez-Payá et al 2015 Neurodynamic test 2 wrist flexions 22 Median Nerve 1 session LNM, PNM, ND DS Resting conditions LNM =32% (3.72mm) PNM =73% (1.58 mm); ND =14% DS=During Stretching; LNG=Longitudinal nerve motion; LNM=Lateral nerve motion; M=Masseter; ND=Nerve deformation; N/A= Not Available; ODI= Oswestry Disability Index; PNM=Posterior nerve motion; PPT=Pressure pain thresholds; PS= Post Stretching; ROM=Range of movement; RT=Resistive torque; SUB=Suboccipitalis; SWVs= Sciatic nerve Shear wave velocity; SWVt= Tibial nerve Shear wave velocity T=Temporalis; TIB=Tibialis; TRAP=Trapezius; VAS=Visual analog scale.