Table 1. Characteristics of the studies included in the network.
Authors Country Sample Size Intervention Method Intervention: Control Age Weeks Weekly Exercise Frequency Time Exercise Program Cognitive Assessment Test Other Indicators
Kwok et al. (2024 Hong Kong, China I: 39 Aquatic HIIT I: 66.3±5.0
C: 65.7±6.2
8 2 20 min Deep water run or run: weeks 1-2 (10 bouts of 2-minute exercise at 80%-85% HRmax + 1-minute active recovery 50% HRmax), weeks 3-5 (10 bouts of 2-minute exercise at 85%-90% HRmax + 1-minute active recovery at 50% HRmax, weeks 6-8 (10 bouts of 2-minute exercise at 90%-95% HRmax + 1-minute active recovery at 50% HRmax. NR MMSE
MoCA
Cardiorespiratory fitness
Triglycerides
Total Cholesterol
HDL
LDL
C: 31 Land-based exercise
Ploydang et al. (2023) Thailand I: 17 Aquatic aerobic exercise I: 69±3.7
C: 69.2±5.3
12 3 60 min Nordic Walking in Water:weeks 1-6(40%–50%HRR), weeks 6-12(50%–60% HRR). MMSE
MoCA
Stroop color test (s)
Trail Making
Test Part B (s)
Vascular function
Cerebrovascular function
Biochemical variables
C: 17 Nonexercising Usual care
Kang et al. (2020) South Korea I: 17 Aquatic aerobic exercise I: 73.8±4.0
C: 73.4±4.2
16 3 60 min Jogging, jumping jacks, cross country, pendulum, and other similar exercises: weeks 1-4 (40%–50%HRR), weeks 5-8 (50%–60% HRR), weeks 9-12 (60%–65%HRR), weeks 13-16 (65%–70%HRR). MMSE-K BDNF
IGF-1
VEGF
BMI
C: 10 Nonexercising Usual care
Jang et al. (2021) South Korea I: 13 Aquatic HIIT I: ≥65
C: ≥65
12 3 40 min Aquatic walking, jumping jack, standing jump, and other similar exercises: Weeks1-12 MMSE-K Triglycerides
HDL
LDL
IGF-1
C: 12 Land-based exercise NR
So et al. (2024) Hong Kong, China I: 14 Aquatic aerobic exercise I: 65.9±0.8
C: 65.9±1.0
NR NR 30 min Both groups performed a 20-minute running exercise. In the Land group, participants ran at a speed and treadmill grade predetermined from a prior incremental test. In the Aquatic group, participants were required to run in the desired cadence, which was monitored by a metronome. DSST Cerebral blood flow
C: 14 Land-based exercise
Sato et al. (2015) Japan I: 7 Aquatic cognitive–motor exercise I: 69-76
C: 69-86
10 1 50 min 10 minutes of walking, 30 minutes of aquatic cognitive exercises, and 10 minutes of water-based stretching and relaxation. HDS-R Physical functions
C: 7 Aquatic strength training 10 minutes of walking, 30 minutes of strength and step exercises (including striding movements), and 10 minutes of water-based stretching and relaxation.
Dunlap et al. (2024) USA I: 13 Aquatic cognitive–motor exercise I: 83±7
C: 81±8
8 3 45 min Aquatic exercise and cognitive training: Weeks1-8 (10-minute warm-up; 25-minute training phase; 10-minute cool-down) Stroop color-word test Neurotrophic factors Functional mobility Balance
C: 12 Nonexercising Usual care
Kooncumchoo et al. (2025) Thailand I: 23 Aquatic cognitive–motor exercise I: 69.4±3.7
C: 68.3±3.3
12 3 60 min 10-min warm-up, 40-min of aerobic exercise, simultaneously with cognitive training involving recalling a number and color, and a 10-min cool-down. MoCA Two MST
BaPWV (cm/s)
C: 23 Aquatic aerobic exercise 10 min of warm-up, 40-min of aerobic exercise(hip flexion and abduction, side back kick, etc), and 10-min cool-down.
Carral et al. (2007) Spain I: 31 Aquatic strength training I: 68.5±3.40
C: 68.3±3.5
9 2 45 min Aquatic exercise: Weeks 1-9 (6 of muscular resistance in the water, 9 of moving in different positions, etc.) + Strength.Training: weeks5-9 (aerobic resistance and mobility of the joints, bodybuilding, etc) MMSE Quality of life Cardiorespiratory fitness
C: 31 Aquatic HIIT Aquatic exercise: Weeks1-9 (6 of muscular resistance in the water, 9 of moving in different positions, etc.) + Calisthenic Training: Weeks5-9(walking, aerobic resistance, etc)
I: Intervention, C: Control, HIIT: high-intensity interval training, NR: Not Reported, HDL: High-Density Lipoprotein, LDL: Low-Density Lipoprotein.