Journal of Sports Science and Medicine
Journal of Sports Science and Medicine
ISSN: 1303 - 2968   
Ios-APP Journal of Sports Science and Medicine
Androit-APP Journal of Sports Science and Medicine
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©Journal of Sports Science and Medicine (2007) 06, 423 - 428

Research article
Exercise Performance and Muscle Contractile Properties After Creatine Monohydrate Supplementation in Aerobic-Anaerobic Training Rats
Nickolay Boyadjiev1, , Dobrin Popov1, Slavi Delchev2
Author Information
1 Department of Physiology, Medical University of Plovdiv, Bulgaria
2 Department of Anatomy, Histology and Embryology, Medical University of Plovdiv, Bulgaria

Nickolay Boyadjiev
✉ Department of Physiology, Medical University, 15-a Vassil Aprilov Blvd., 4000 Plovdiv, BULGARIA
Email: boyad@plov.net
Publish Date
Received: 19-03-2007
Accepted: 02-07-2007
Published (online): 01-12-2007
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ABSTRACT

The purpose of this study was to investigate the effects of creatine monohydrate supplementation on exercise performance and contractile variables in aerobic-anaerobic training rats. Twenty 90-day-old male Sprague Dawley rats were divided into two groups - creatine (Cr) and controls (K). The creatine group received creatine monohydrate as a nutritional supplement, whereas the control group was given placebo. Both groups were trained 5 days a week on a treadmill for 20 days in a mixed (aerobic-anaerobic) metabolic working regimen (27 m·min-1, 15% elevation for 40 min). The exercise performance (sprint-test), contractile properties (m. tibialis anterior), oxidative enzyme activity (SDH, LDH, NADH2) in m. soleus and blood hematological and chemical variables were assessed in the groups at the end of the experiment. It was found out that creatine supplementation improved the exercise performance after 20 days of administration in a dose of 60 mg per day on the background of a mixed (aerobic-anaerobic) exercise training. At the end of the trial the Cr-group demonstrated better values for the variables which characterize the contractile properties of m. tibialis anterior containing predominantly types IIA and IIB muscle fibers. On the other hand, a higher oxidative capacity was found out in m. soleus (type I muscle fibers) as a result of 20-day creatine supplementation. No side effects of creatine monohydrate supplementation were assessed by the hematological and blood biochemical indices measured in this study.

Key words: Exercise, creatine supplementation, rats, performance, muscle contractile properties


           Key Points
  • The creatine monohydrate supplementation of the rats diet improves their exercise performance after 20 days administration in a dose of 60 mg per day on the background of a mixed (aerobic-anaerobic) exercise training.
  • The creatine supplemented rats demonstrate better contractile properties of m. tibialis anterior which muscle contains predominantly types IIA and IIB muscle fibers.
  • The soleus muscle (type I muscle fibers) demonstrates a higher oxidative capacity as a result of 20-days creatine supplementation.
 
 
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