Journal of Sports Science and Medicine
Journal of Sports Science and Medicine
ISSN: 1303 - 2968   
Ios-APP Journal of Sports Science and Medicine
Androit-APP Journal of Sports Science and Medicine
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©Journal of Sports Science and Medicine (2011) 10, 649 - 654

Research article
Effects of exercise and caffeic acid phenethyl ester after chronic exercise rat model
Ayse Alp1, Sadik Buyukbas2, Harun Alp3, , H. Serdar Gergerlioglu4, Mehmet Oz5, M. Kemal Basarali6, Aysel Kiyici7
Author Information
1 Diyarbakir Training and Research Hospital, Biochemistry Department, Diyarbakir, Turkey
2 Selcuk University, Konya, Turkey
3 Dicle University, Diyarbakir, Turkey
4 Selcuk University, Konya, Turkey
5 Selcuk University, Konya, Turkey
6 Dicle University, Diyarbakir, Turkey
7 Selcuk University, Konya, Turkey

Harun Alp
‚úČ Department of Pharmacology and Toxicology, Veterinary Faculty, Dicle University, Diyarbakir, Turkey
Email: alpharun@gmail.com
Publish Date
Received: 30-05-2011
Accepted: 25-08-2011
Published (online): 01-12-2011
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ABSTRACT

In order to understand whether exercise and caffeic acid phenethyl ester (CAPE) has an effect on obesity and weight control, we investigated the effects of CAPE, and exercise on lipid parameters (triglyceride, total cholesterol, HDL-C, LDL-C), and adipokine substances such as leptin and resistin in rats. 40 male rat were randomly assigned into 4 groups. It was determined that CAPE does not have any significant effect on these parameters but that lipid parameters and leptin values in exercise groups decreased considerably, while no significant change occurred in resistin levels. In order to understand whether diet has an effect on exercise, body weights of all animal groups in pre and post-exercise were compared. A significant weight gain was observed (p = 0.005) in all groups. This study concluded that exercise has a considerable effect on leptin and lipid parameters; however, exercise alone was not sufficient for weight control and could be effective in weight control only when accompanied by a restricted diet.

Key words: Caffeic acid phenethyl ester, exercise, leptin, resistin, weight control


           Key Points
  • Caffeic acid phenethyl ester is not effective on weight control, lipid parameters, and adipokine substances such as leptin and resistin.
  • Exercise can be effective in weight control only when accompanied by a restricted diet.
 
 
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