Journal of Sports Science and Medicine
Journal of Sports Science and Medicine
ISSN: 1303 - 2968   
Ios-APP Journal of Sports Science and Medicine
Androit-APP Journal of Sports Science and Medicine
©Journal of Sports Science and Medicine (2014) 13, 680 - 688

Research article
Effects of Resistance Training on Muscle Strength, Endurance, and Motor Unit According to Ciliary Neurotrophic Factor Polymorphism in Male College Students
Ae-Rim Hong1, Sang-Min Hong2, Yun-A Shin1, 
Author Information
1 Department of Exercise Prescription & Rehabilitation, College of Sports Science, Dankook University, Anseo-dong, Cheonan-si, Chungnam Republic of Korea
2 Department of Physical Education, College of Education, Dongguk University, Pildong-ro-1-gil, Jung-gu, Seoul, Republic of Korea

Yun-A Shin
✉ Department of Exercise Prescription & Rehabilitation, College of Sports Science, and Department of Kinesiologic Medical Science, Graduate School, Dankook University, San 29, Anseo-dong, Cheonan-si, Chungnam 330-714, Republic of Korea
Publish Date
Received: 14-02-2014
Accepted: 16-06-2014
Published (online): 01-09-2014
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Changes in muscle mass and strength across the adult age span are variable and related to the ciliary neurotrophic factor (CNTF) genotype. In particular, a single CNTF haplotype (1357 G→A) is important for neuronal and muscular developments and may be associated with muscle strength response to resistance training. We examined whether CNTF genotype differentially influences the effect of resistance training on neuromuscular improvement in male college students. Resistance training of the upper extremities comprised 3 sets at 75%–85% intensity per 1 repetition maximum, 3 times a week, for a total of 8 weeks. We measured isokinetic muscle function of the elbow joint with regard to strength (60°/s) and endurance (180°/s) by using an isokinetic dynamometer. The biceps brachii (BB) and brachioradialis muscles were studied using surface electromyography with spike-triggered averaging to assess surface-detected motor unit potential (SMUP) area. After resistance training, the SMUP of the BB increased significantly at 60°/s (p < 0.05), but no difference in the CNTF genotype was observed. The SMUP of the BB at 180°/s increased significantly in the GG/AA genotype group compared with that in the GA genotype group (p < 0.05). The average power of the elbow flexor at 180°/s increased significantly after resistance training (p < 0.05), but again, no difference in the CNTF genotype was observed. Thus, improvements in muscle strength and endurance may have resulted directly from resistance training rather than from genetic factors related to nerves in muscle tissue.

Key words: Resistance training, muscle strength, muscle endurance, motor unit, ciliary neurotrophic factor genotype

           Key Points
  • Resistance training improves muscle strength and endurance in young men.
  • This improvement in muscular strength and endurance is irrespective of CNTF genotypes.
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